David A Yarmolinsky
Overview
Explore the profile of David A Yarmolinsky including associated specialties, affiliations and a list of published articles.
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9
Citations
839
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Recent Articles
1.
Yarmolinsky D, Zeng X, MacKinnon-Booth N, Greene C, Kim C, Cheng Y, et al.
Neuron
. 2025 Mar;
PMID: 40023166
Pain hypersensitivity arises from the induction of plasticity in peripheral and spinal somatosensory neurons, which modifies nociceptive input to the brain, altering pain perception. We applied longitudinal calcium imaging of...
2.
Barkai O, Zhang B, Lenfers Turnes B, Arab M, Yarmolinsky D, Zhang Z, et al.
bioRxiv
. 2024 Dec;
PMID: 39677681
A detailed analysis of pain-related behaviors in rodents is essential for exploring both the mechanisms of pain and evaluating analgesic efficacy. With the advancement of pose-estimation tools, automatic single-camera video...
3.
Flayer C, Kernin I, Matatia P, Zeng X, Yarmolinsky D, Han C, et al.
Nature
. 2024 Sep;
634(8033):440-446.
PMID: 39232162
In naive individuals, sensory neurons directly detect and respond to allergens, leading to both the sensation of itch and the activation of local innate immune cells, which initiate the allergic...
4.
Yarmolinsky D, Zeng X, MacKinnon-Booth N, Greene C, Kim C, Woolf C
bioRxiv
. 2024 Apr;
PMID: 38645252
Pain hypersensitivity arises from the plasticity of peripheral and spinal somatosensory neurons, which modifies nociceptive input to the brain and alters pain perception. We utilized chronic calcium imaging of spinal...
5.
Zhang Z, Roberson D, Kotoda M, Boivin B, Bohnslav J, Gonzalez-Cano R, et al.
Pain
. 2022 May;
163(12):2326-2336.
PMID: 35543646
The lack of sensitive and robust behavioral assessments of pain in preclinical models has been a major limitation for both pain research and the development of novel analgesics. Here, we...
6.
Bohnslav J, Wimalasena N, Clausing K, Dai Y, Yarmolinsky D, Cruz T, et al.
Elife
. 2021 Sep;
10.
PMID: 34473051
Videos of animal behavior are used to quantify researcher-defined behaviors of interest to study neural function, gene mutations, and pharmacological therapies. Behaviors of interest are often scored manually, which is...
7.
Yarmolinsky D, Peng Y, Pogorzala L, Rutlin M, Hoon M, Zuker C
Neuron
. 2016 Nov;
92(5):1079-1092.
PMID: 27840000
Perception of the thermal environment begins with the activation of peripheral thermosensory neurons innervating the body surface. To understand how temperature is represented in vivo, we used genetically encoded calcium...
8.
Barretto R, Gillis-Smith S, Chandrashekar J, Yarmolinsky D, Schnitzer M, Ryba N, et al.
Nature
. 2014 Nov;
517(7534):373-6.
PMID: 25383521
The mammalian taste system is responsible for sensing and responding to the five basic taste qualities: sweet, sour, bitter, salty and umami. Previously, we showed that each taste is detected...
9.
Chandrashekar J, Kuhn C, Oka Y, Yarmolinsky D, Hummler E, Ryba N, et al.
Nature
. 2010 Jan;
464(7286):297-301.
PMID: 20107438
Salt taste in mammals can trigger two divergent behavioural responses. In general, concentrated saline solutions elicit robust behavioural aversion, whereas low concentrations of NaCl are typically attractive, particularly after sodium...
10.
Yarmolinsky D, Zuker C, Ryba N
Cell
. 2009 Oct;
139(2):234-44.
PMID: 19837029
The sense of taste is a specialized chemosensory system dedicated to the evaluation of food and drink. Despite the fact that vertebrates and insects have independently evolved distinct anatomic and...