David A Skerrett-Byrne
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Explore the profile of David A Skerrett-Byrne including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
292
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Recent Articles
1.
Perera T, de Ruijter-Villani M, Gibb Z, Nixon B, Sheridan A, Stout T, et al.
Proteomics Clin Appl
. 2025 Feb;
19(2):e202400095.
PMID: 39912552
Purpose: Embryo-maternal signaling during the establishment of pregnancy in horses remains one of the biggest mysteries in large animal physiology. Early pregnancy loss represents a major source of economic loss...
2.
Trigg N, Schjenken J, Martin J, Skerrett-Byrne D, Smyth S, Bernstein I, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(47):e2409790121.
PMID: 39527742
Forecasted increases in the prevalence and severity of extreme weather events accompanying changes in climatic behavior pose potential risk to the reproductive capacity of humans and animals of ecological and...
3.
Perera T, Bromfield E, Gibb Z, Nixon B, Sheridan A, Rupasinghe T, et al.
Int J Mol Sci
. 2024 Oct;
25(20).
PMID: 39456856
Understanding the systemic biochemistry of early pregnancy in the mare is essential for developing new diagnostics and identifying causes for pregnancy loss. This study aimed to elucidate the dynamic lipidomic...
4.
Skerrett-Byrne D, Teperino R, Nixon B
Reprod Fertil Dev
. 2024 Aug;
36.
PMID: 39088693
Context Integrated omics studies hold a crucial role in improving our understanding of reproductive biology. However, the complex datasets so generated are often only accessible via supplementary data files, which...
5.
Phosphoproteomic analysis of the adaption of epididymal epithelial cells to corticosterone challenge
Skerrett-Byrne D, Stanger S, Trigg N, Anderson A, Sipila P, Bernstein I, et al.
Andrology
. 2024 Apr;
12(5):1038-1057.
PMID: 38576152
Background: The epididymis has long been of interest owing to its role in promoting the functional maturation of the male germline. More recent evidence has also implicated the epididymis as...
6.
Duchatel R, Jackson E, Parackal S, Kiltschewskij D, Findlay I, Mannan A, et al.
J Clin Invest
. 2024 Feb;
134(6).
PMID: 38319732
Diffuse midline glioma (DMG), including tumors diagnosed in the brainstem (diffuse intrinsic pontine glioma; DIPG), are uniformly fatal brain tumors that lack effective treatment. Analysis of CRISPR/Cas9 loss-of-function gene deletion...
7.
Smyth S, Nixon B, Skerrett-Byrne D, Burke N, Bromfield E
Antioxid Redox Signal
. 2023 Dec;
41(4-6):296-321.
PMID: 38115641
Stringent regulation of protein homeostasis pathways, under both physiological and pathological conditions, is necessary for the maintenance of proteome fidelity and optimal cell functioning. However, when challenged by endogenous or...
8.
Chen Y, Roselli S, Panicker N, Brzozowski J, Skerrett-Byrne D, Murray H, et al.
Proteomics
. 2023 Oct;
24(7):e2300267.
PMID: 37849217
Fibroblasts are the most common cell type in stroma and function in the support and repair of most tissues. Mouse embryonic fibroblasts (MEFs) are amenable to isolation and rapid growth...
9.
Mulhall J, Trigg N, Bernstein I, Anderson A, Murray H, Sipila P, et al.
Proteomics
. 2023 Sep;
24(7):e2300253.
PMID: 37759396
Residing between the testes and the vas deferens, the epididymis is a highly convoluted tubule whose unique luminal microenvironment is crucial for the functional maturation of spermatozoa. This microenvironment is...
10.
Jackson E, Duchatel R, Staudt D, Persson M, Mannan A, Yadavilli S, et al.
Cancer Res
. 2023 May;
:OF1-OF17.
PMID: 37195023
Significance: PI3K/Akt signaling promotes metabolic adaptation to ONC201-mediated disruption of mitochondrial energy homeostasis in diffuse intrinsic pontine glioma, highlighting the utility of a combination treatment strategy using ONC201 and the...