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David A Simpson

Explore the profile of David A Simpson including associated specialties, affiliations and a list of published articles. Areas
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Articles 79
Citations 2035
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Recent Articles
1.
Rice A, Troendle E, Bridgett S, Firoozi Nejad B, McKinley J, Bradley D, et al.
Genome Med . 2024 Dec; 16(1):150. PMID: 39702217
Background: Ireland's COVID-19 response combined extensive SARS-CoV-2 testing to estimate incidence, with whole genome sequencing (WGS) for genome surveillance. As an island with two political jurisdictions-Northern Ireland (NI) and Republic...
2.
Lee A, Carson S, Reyne M, Marshall A, Moody D, Allen D, et al.
Lancet Microbe . 2024 Oct; 5(12):100933. PMID: 39395428
Background: Influenza A viruses (IAVs) are significant pathogens of humans and other animals. Although endemic in humans and birds, novel IAV strains can emerge, jump species, and cause epidemics, like...
3.
Stewart A, Zhu Y, Liu Y, Simpson D, Reece P
Nano Lett . 2024 Sep; 24(39):12188-12195. PMID: 39291712
Here we show that gradient force optical tweezers can be used to mediate the self-assembly of nanodiamonds into superstructures, which can serve as optically trapped nanoscale quantum probes with superior...
4.
Doyle C, Callaghan B, Roodnat A, Armstrong L, Lester K, Simpson D, et al.
Cells . 2024 Jun; 13(12. PMID: 38920689
Primary open-angle glaucoma (POAG) is a progressive optic neuropathy with a complex, multifactorial aetiology. Raised intraocular pressure (IOP) is the most important clinically modifiable risk factor for POAG. All current...
5.
Russell-Hallinan A, Cappa O, Kerrigan L, Tonry C, Edgar K, Glezeva N, et al.
Cells . 2024 May; 13(9. PMID: 38727290
Dilated cardiomyopathy (DCM) is the most common cause of heart failure, with a complex aetiology involving multiple cell types. We aimed to detect cell-specific transcriptomic alterations in DCM through analysis...
6.
Silk R, Winter H, Dkhissi-Benyahya O, Evans-Molina C, Stitt A, Tiwari V, et al.
Vision Res . 2023 Dec; 214:108339. PMID: 38039846
Retinal function changes dramatically from day to night, yet clinical diagnosis, treatments, and experimental sampling occur during the day. To begin to address this gap in our understanding of disease...
7.
Elliott T, Spalink D, Larridon I, Zuntini A, Escudero M, Hackel J, et al.
New Phytol . 2023 Nov; 242(2):727-743. PMID: 38009920
Poales are one of the most species-rich, ecologically and economically important orders of plants and often characterise open habitats, enabled by unique suites of traits. We test six hypotheses regarding...
8.
Emri E, Cappa O, Kelly C, Kortvely E, SanGiovanni J, McKay B, et al.
Cells . 2023 Mar; 12(5). PMID: 36899910
Zinc supplementation has been shown to be beneficial to slow the progression of age-related macular degeneration (AMD). However, the molecular mechanism underpinning this benefit is not well understood. This study...
9.
Grant E, Hall L, Hollenberg L, McColl G, Simpson D
ACS Nano . 2022 Dec; 17(1):372-381. PMID: 36534782
Ferritin is the primary storage protein in our body and is of significant interest in biochemistry, nanotechnology, and condensed matter physics. More specifically within this sphere of interest are the...
10.
Roodnat A, Callaghan B, Doyle C, Henry M, Goljanek-Whysall K, Simpson D, et al.
Biomolecules . 2022 Nov; 12(11). PMID: 36421707
Pseudoexfoliation glaucoma (XFG) is an aggressive form of secondary open angle glaucoma, characterised by the production of exfoliation material and is estimated to affect 30 million people worldwide. Activation of...