David A Russler-Germain
Overview
Explore the profile of David A Russler-Germain including associated specialties, affiliations and a list of published articles.
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30
Citations
725
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Recent Articles
1.
Zhou A, Marin N, Afrin S, Wong P, Tran J, Jacobs M, et al.
J Immunol
. 2025 Mar;
214(1):1-11.
PMID: 40073259
Natural killer (NK) cells are a promising approach for cellular cancer immunotherapy and are being investigated to treat patients with multiple myeloma (MM). We found that MM patient blood NK...
2.
Russler-Germain D, Bartlett N
Hematology Am Soc Hematol Educ Program
. 2024 Dec;
2024(1):310-317.
PMID: 39643999
Treatment for relapsed/refractory (R/R) follicular lymphoma (FL) has evolved over recent years with the introduction of multiple novel immunotherapies: anti-CD3 × CD20 bispecific antibody (BsAb) T-cell engagers and anti-CD19 chimeric...
3.
Kakkilaya A, Trando A, Cliff E, Mian H, Al Hadidi S, Aziz M, et al.
Oncologist
. 2024 Sep;
30(2).
PMID: 39236068
Background: Smoldering multiple myeloma (SMM), an asymptomatic precursor of multiple myeloma (MM), carries a variable risk of progression to MM. There is little consensus on the efficacy or optimal timing...
4.
Cliff E, Russler-Germain D, Daval C, Kesselheim A
J Clin Oncol
. 2024 Jul;
42(33):3901-3904.
PMID: 39052948
The FDA's directive to deal with delayed confirmatory trials: lessons from pralatrexate and belinostat for T-cell lymphoma.
5.
Foltz J, Tran J, Wong P, Fan C, Schmidt E, Fisk B, et al.
Sci Immunol
. 2024 Jun;
9(96):eadk4893.
PMID: 38941480
Activation of natural killer (NK) cells with the cytokines interleukin-12 (IL-12), IL-15, and IL-18 induces their differentiation into memory-like (ML) NK cells; however, the underlying epigenetic and transcriptional mechanisms are...
6.
Cubitt C, Wong P, Dorando H, Foltz J, Tran J, Marsala L, et al.
J Clin Invest
. 2024 May;
134(15).
PMID: 38805302
The surface receptor CD8α is present on 20%-80% of human (but not mouse) NK cells, yet its function on NK cells remains poorly understood. CD8α expression on donor NK cells...
7.
Marin N, Becker-Hapak M, Song W, Alayo Q, Marsala L, Sonnek N, et al.
Oncoimmunology
. 2024 May;
13(1):2348254.
PMID: 38737793
Metastatic (m) colorectal cancer (CRC) is an incurable disease with a poor prognosis and thus remains an unmet clinical need. Immune checkpoint blockade (ICB)-based immunotherapy is effective for mismatch repair-deficient...
8.
Ramirez C, Becker-Hapak M, Singhal K, Russler-Germain D, Frenkel F, Barnell E, et al.
Blood Adv
. 2024 May;
8(15):4035-4049.
PMID: 38713894
Personalized cancer vaccines designed to target neoantigens represent a promising new treatment paradigm in oncology. In contrast to classical idiotype vaccines, we hypothesized that "polyvalent" vaccines could be engineered for...
9.
Alrawabdeh J, Alzubi M, Alzyoud M, Odeh N, Hamadneh Y, Mian H, et al.
JNCI Cancer Spectr
. 2023 Nov;
7(6).
PMID: 38006333
Background: Subgroup analyses in clinical trials assess intervention effects on specific patient subgroups, ensuring generalizability. However, they are usually only able to generate hypotheses rather than definitive conclusions. This study...
10.
Gomez F, Fisk B, McMichael J, Mosior M, Foltz J, Skidmore Z, et al.
Cancer Res Commun
. 2023 Nov;
3(11):2312-2330.
PMID: 37910143
Significance: Our data demonstrate the utility of ultra-deep exome sequencing in uncovering somatic variants in Hodgkin lymphoma, creating new opportunities to define the genes that are recurrently mutated in this...