David A Lane
Overview
Explore the profile of David A Lane including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
61
Citations
1339
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Carollo R, Lane D, Kleiner E, Kyaw P, Teng C, Ou C, et al.
Opt Express
. 2017 Apr;
25(7):7220-7229.
PMID: 28380847
We generate coherent ultraviolet radiation at 313 nm as the third harmonic of an external-cavity diode laser. We use this radiation for laser cooling of trapped beryllium atomic ions and...
12.
South K, Freitas M, Lane D
J Biol Chem
. 2017 Feb;
292(14):5760-5769.
PMID: 28209710
Blood loss is prevented by the multidomain glycoprotein von Willebrand factor (VWF), which binds exposed collagen at damaged vessels and captures platelets. VWF is regulated by the metalloprotease ADAMTS13, which...
13.
14.
Lane D
Philos Trans R Soc Lond B Biol Sci
. 2016 Mar;
371(1690).
PMID: 26926284
Innovation cascades inextricably link the introduction of new artefacts, transformations in social organization, and the emergence of new functionalities and new needs. This paper describes a positive feedback dynamic, exaptive...
15.
Lynch C, Lane D
Blood
. 2016 Jan;
127(13):1711-8.
PMID: 26773038
Shear forces in the blood trigger a conformational transition in the von Willebrand factor (VWF) A2 domain, from its native folded to an unfolded state, in which the cryptic scissile...
16.
Andreou A, Efthymiou M, Yu Y, Watts H, Noormohamed F, Ma D, et al.
PLoS One
. 2015 Apr;
10(4):e0122410.
PMID: 25830552
Ischaemic stroke is caused by occlusive thrombi in the cerebral vasculature. Although tissue-plasminogen activator (tPA) can be administered as thrombolytic therapy, it has major limitations, which include disruption of the...
17.
de Groot R, Lane D, Crawley J
Blood
. 2015 Jan;
125(12):1968-75.
PMID: 25564400
ADAMTS13 proteolytically regulates the platelet-tethering function of von Willebrand factor (VWF). ADAMTS13 function is dependent upon multiple exosites that specifically bind the unraveled VWF A2 domain and enable proteolysis. We...
18.
South K, Luken B, Crawley J, Phillips R, Thomas M, Collins R, et al.
Proc Natl Acad Sci U S A
. 2014 Dec;
111(52):18578-83.
PMID: 25512499
A disintegrin and metalloprotease with thrombospondin motifs 13 (ADAMTS13) is a metalloprotease that regulates von Willebrand factor (VWF) function. ADAMTS13-mediated proteolysis is determined by conformational changes in VWF, but also...
19.
Reglinska-Matveyev N, Andersson H, Rezende S, Dahlback B, Crawley J, Lane D, et al.
Blood
. 2014 Apr;
123(25):3979-87.
PMID: 24740810
Protein S is a cofactor for tissue factor pathway inhibitor (TFPI), accelerating the inhibition of activated factor X (FXa). TFPI Kunitz domain 3 residue Glu226 is essential for enhancement of...
20.
Salles-Crawley I, Monkman J, Ahnstrom J, Lane D, Crawley J
Blood
. 2014 Mar;
123(18):2873-81.
PMID: 24627527
Bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) is a transmembrane protein related to the transforming growth factor-β superfamily, and is highly expressed in platelets and endothelial cells. We previously...