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David A DeSantis

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Citations 51
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Recent Articles
1.
DeSantis D, Ko C, Wang L, Lee P, Croniger C
Mediators Inflamm . 2015 Dec; 2015:909827. PMID: 26635450
TThe molecular mechanisms responsible for the development of hepatic fibrosis are not fully understood. The Nlrc4 inflammasome detects cytosolic presence of bacterial components, activating inflammatory cytokines to facilitate clearance of...
2.
Gao Y, Erokwu B, DeSantis D, Croniger C, Schur R, Lu L, et al.
NMR Biomed . 2015 Nov; 29(1):84-9. PMID: 26608869
Autosomal recessive polycystic kidney disease (ARPKD) is a potentially lethal multi-organ disease affecting both the kidneys and the liver. Unfortunately, there are currently no non-invasive methods to monitor liver disease...
3.
DeSantis D, Ko C, Liu Y, Liu X, Hise A, Nunez G, et al.
Mediators Inflamm . 2014 Jan; 2013:751374. PMID: 24453428
Alcoholic liver disease (ALD) is characterized by increased hepatic lipid accumulation (steatosis) and inflammation with increased expression of proinflammatory cytokines. Two of these cytokines, interleukin-1 β (IL-1 β ) and...
4.
DeSantis D, Lee P, Doerner S, Ko C, Kawasoe J, Hill-Baskin A, et al.
Alcohol Clin Exp Res . 2013 Jun; 37(10):1668-79. PMID: 23763294
Background: Because the histological and biochemical progression of liver disease is similar in alcoholic steatohepatitis (ASH) and nonalcoholic steatohepatitis (NASH), we hypothesized that the genetic susceptibility to these liver diseases...