Dave Beare
Overview
Explore the profile of Dave Beare including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
3116
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Recent Articles
1.
Yang W, Soares J, Greninger P, Edelman E, Lightfoot H, Forbes S, et al.
Nucleic Acids Res
. 2012 Nov;
41(Database issue):D955-61.
PMID: 23180760
Alterations in cancer genomes strongly influence clinical responses to treatment and in many instances are potent biomarkers for response to drugs. The Genomics of Drug Sensitivity in Cancer (GDSC) database...
2.
Dalgliesh G, Furge K, Greenman C, Chen L, Bignell G, Butler A, et al.
Nature
. 2010 Jan;
463(7279):360-3.
PMID: 20054297
Clear cell renal cell carcinoma (ccRCC) is the most common form of adult kidney cancer, characterized by the presence of inactivating mutations in the VHL gene in most cases, and...
3.
Greenman C, Bignell G, Butler A, Edkins S, Hinton J, Beare D, et al.
Biostatistics
. 2009 Oct;
11(1):164-75.
PMID: 19837654
High-throughput oligonucleotide microarrays are commonly employed to investigate genetic disease, including cancer. The algorithms employed to extract genotypes and copy number variation function optimally for diploid genomes usually associated with...
4.
van Haaften G, Dalgliesh G, Davies H, Chen L, Bignell G, Greenman C, et al.
Nat Genet
. 2009 Mar;
41(5):521-3.
PMID: 19330029
Somatically acquired epigenetic changes are present in many cancers. Epigenetic regulation is maintained via post-translational modifications of core histones. Here, we describe inactivating somatic mutations in the histone lysine demethylase...