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Dat P Mao

Explore the profile of Dat P Mao including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 1494
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Recent Articles
1.
Miao E, Leaf I, Treuting P, Mao D, Dors M, Sarkar A, et al.
Nat Immunol . 2010 Nov; 11(12):1136-42. PMID: 21057511
Macrophages mediate crucial innate immune responses via caspase-1-dependent processing and secretion of interleukin 1β (IL-1β) and IL-18. Although infection with wild-type Salmonella typhimurium is lethal to mice, we show here...
2.
Warren S, Armstrong A, Hamilton M, Mao D, Leaf I, Miao E, et al.
J Immunol . 2010 Jun; 185(2):818-21. PMID: 20562263
Pathogens are detected by pattern recognition receptors that, upon activation, orchestrate an appropriate immune response. The TLRs and the nucleotide-binding oligomerization domain-like receptors (NLRs) are prototypic pattern recognition receptors that...
3.
Miao E, Mao D, Yudkovsky N, Bonneau R, Lorang C, Warren S, et al.
Proc Natl Acad Sci U S A . 2010 Feb; 107(7):3076-80. PMID: 20133635
The mammalian innate immune system uses Toll-like receptors (TLRs) and Nod-LRRs (NLRs) to detect microbial components during infection. Often these molecules work in concert; for example, the TLRs can stimulate...
4.
Warren S, Mao D, Rodriguez A, Miao E, Aderem A
J Immunol . 2008 May; 180(11):7558-64. PMID: 18490757
Listeria monocytogenes escapes from the phagosome of macrophages and replicates within the cytosolic compartment. The macrophage responds to L. monocytogenes through detection pathways located on the cell surface (TLRs) and...
5.
Miao E, Ernst R, Dors M, Mao D, Aderem A
Proc Natl Acad Sci U S A . 2008 Feb; 105(7):2562-7. PMID: 18256184
The innate immune system encodes cytosolic Nod-like receptors (NLRs), several of which activate caspase 1 processing and IL-1beta and IL-18 secretion. Macrophages respond to Salmonella typhimurium infection by activating caspase...