Darwin J Prockop
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Explore the profile of Darwin J Prockop including associated specialties, affiliations and a list of published articles.
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132
Citations
13563
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Recent Articles
1.
Kodali M, Castro O, Kim D, Thomas A, Shuai B, Attaluri S, et al.
Int J Mol Sci
. 2020 Jan;
21(1).
PMID: 31888012
Extracellular vesicles (EVs) derived from human bone marrow mesenchymal stem cells (hMSCs) have great promise as biologics to treat neurological and neurodegenerative conditions due to their robust antiinflammatory and neuroprotective...
2.
Nepal S, Tiruppathi C, Tsukasaki Y, Farahany J, Mittal M, Rehman J, et al.
Proc Natl Acad Sci U S A
. 2019 Aug;
116(33):16513-16518.
PMID: 31363052
Efferocytosis of apoptotic neutrophils (PMNs) by alveolar macrophages (AMФs) is vital for resolution of inflammation and tissue injury. Here, we investigated the role of AMФ polarization and expression of the...
3.
Choi H, Phillips C, Oh J, Potts L, Reger R, Prockop D, et al.
Curr Eye Res
. 2019 Apr;
44(8):873-881.
PMID: 30935217
: To investigate the therapeutic efficacy of tumor necrosis factor (TNF)-α stimulated gene/protein 6 (TSG-6) in a rat model of corneal alkali injury. : Corneal alkali injury was produced by...
4.
Pacienza N, Lee R, Bae E, Kim D, Liu Q, Prockop D, et al.
Mol Ther Methods Clin Dev
. 2019 Feb;
13:67-76.
PMID: 30719485
Extracellular vesicles (EVs) play key roles in cell biology and may provide new clinical diagnostics and therapies. However, it has proven difficult to develop protocols for their purification and characterization....
5.
Upadhya D, Hattiangady B, Castro O, Shuai B, Kodali M, Attaluri S, et al.
Proc Natl Acad Sci U S A
. 2018 Dec;
116(1):287-296.
PMID: 30559206
Medial ganglionic eminence (MGE)-like interneuron precursors derived from human induced pluripotent stem cells (hiPSCs) are ideal for developing patient-specific cell therapy in temporal lobe epilepsy (TLE). However, their efficacy for...
6.
Prockop D
J Cell Biochem
. 2018 Jan;
72 Suppl 30-31(S30-31):284-285.
PMID: 29345820
No abstract available.
7.
Song H, Park S, Ko J, Park J, Yoon C, Kim D, et al.
Mol Ther
. 2018 Jan;
26(1):162-172.
PMID: 29301108
The cornea is a transparent tissue devoid of blood and lymphatic vessels. However, various inflammatory conditions can cause hemangiogenesis and lymphangiogenesis in the cornea, compromising transparency and visual acuity. Mesenchymal...
8.
Prockop D, Oh J, Lee R
Mol Ther
. 2017 Jun;
25(8):1748-1756.
PMID: 28647464
Much of what we know about immunology suggests that little is to be gained from experiments in which human cells are administered to immunocompetent mice. Multiple reports have demonstrated that...
9.
Shigemoto-Kuroda T, Oh J, Kim D, Jeong H, Park S, Lee H, et al.
Stem Cell Reports
. 2017 May;
8(5):1214-1225.
PMID: 28494937
Accumulating evidence shows that extracellular vesicles (EVs) produced by mesenchymal stem/stromal cells (MSCs) exert their therapeutic effects in several disease models. We previously demonstrated that MSCs suppress autoimmunity in models...
10.
Long Q, Upadhya D, Hattiangady B, Kim D, An S, Shuai B, et al.
Proc Natl Acad Sci U S A
. 2017 Apr;
114(17):E3536-E3545.
PMID: 28396435
Status epilepticus (SE), a medical emergency that is typically terminated through antiepileptic drug treatment, leads to hippocampus dysfunction typified by neurodegeneration, inflammation, altered neurogenesis, as well as cognitive and memory...