Daru Lu
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Explore the profile of Daru Lu including associated specialties, affiliations and a list of published articles.
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Articles
266
Citations
5017
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Recent Articles
1.
Chen S, Wang L, Hu Y, Yao Y, Gao F, Chang C, et al.
BMC Med Genomics
. 2025 Feb;
18(1):34.
PMID: 39984972
Background: To investigate whether the noninvasive preimplantation genetic testing (niPGT) complement conventional preimplantation genetic testing (PGT) in the embryos for aneuploidy. Results: 40 spent culture medium (SCM) samples from routine...
2.
Zhang S, Wu Q, He W, Zhu H, Wang Z, Liang H, et al.
Gene
. 2025 Jan;
941():149210.
PMID: 39755265
Bisphenol A (BPA) is a widely used industrial compound commonly found in various everyday plastic products. Known for its endocrine-disrupting properties, BPA can enter the human body through multiple pathways....
3.
Zhang S, Gao Y, Wang X, Li Q, Tan J, Liang B, et al.
EBioMedicine
. 2024 Dec;
111():105514.
PMID: 39708428
Background: Preimplantation genetic testing for chromosomal structural rearrangements (PGT-SR) has been widely utilized to select euploid embryos in patients carrying balanced chromosomal rearrangements (BCRs) by chromosome copy number analysis. However,...
4.
Long Y, Zhang Q, Ling L, Zhuang Y, Wei X, Huang H, et al.
Blood
. 2024 Dec;
145(10):1074-1088.
PMID: 39693613
Accumulation of free α-globin is a critical factor in the pathogenesis of β-thalassemia. Autophagy plays a crucial role in clearing toxic free α-globin, thereby reducing disease severity. However, the impact...
5.
Blechter B, Hsiung C, Wang X, Zhang H, Seow W, Shi J, et al.
J Thorac Oncol
. 2024 Nov;
PMID: 39581378
We assessed the association between a genome-wide polygenic risk score (PRS) developed for lung adenocarcinoma (LUAD) risk and mutation on the EGFR gene in 998 East Asian never-smoking female LUAD...
6.
Blechter B, Wang X, Shi J, Shiraishi K, Choi J, Matsuo K, et al.
medRxiv
. 2024 Jul;
PMID: 38978671
Polygenic risk scores (PRSs) are promising for risk stratification but have mainly been developed in European populations. This study developed single- and multi-ancestry PRSs for lung adenocarcinoma (LUAD) in East...
7.
Li Y, Yan X, Luo Z, Fu X, Li Z, Xu Q, et al.
Int J Nephrol Renovasc Dis
. 2024 Jun;
17:167-174.
PMID: 38855711
Introduction: X-linked Alport syndrome (XLAS) is caused by pathogenic variants in which lead to abnormalities of the glomerular basement membrane (GBM) structural and is characterized by progressive kidney disease, hearing...
8.
Ye L, Wang C, Li A, Li M, Pi Y, Yang J, et al.
BMC Genomics
. 2024 Mar;
25(1):230.
PMID: 38429690
Background: Krüppel-like factor 1 (KLF1), a crucial erythroid transcription factor, plays a significant role in various erythroid changes and haemolytic diseases. The rare erythrocyte Lutheran inhibitor (In(Lu)) blood group phenotype...
9.
Tian Y, Li M, Yang J, Chen H, Lu D
Arch Gynecol Obstet
. 2024 Feb;
309(5):1787-1799.
PMID: 38376520
Background: Preimplantation genetic testing (PGT), also referred to as preimplantation genetic diagnosis (PGD), is an advanced reproductive technology used during in vitro fertilization (IVF) cycles to identify genetic abnormalities in...
10.
Yang X, Zheng X, Zhu Y, Zhao X, Liu J, Xun J, et al.
Signal Transduct Target Ther
. 2024 Feb;
9(1):42.
PMID: 38355848
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes multi-organ damage, which includes hepatic dysfunction, as observed in over 50% of COVID-19 patients. Angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 (ACE2)...