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Darragh Murnane

Explore the profile of Darragh Murnane including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 103
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Recent Articles
1.
Nguyen T, Ma C, Styliari I, Gajjar P, Hammond R, Withers P, et al.
J Pharm Sci . 2024 Oct; 114(1):507-519. PMID: 39481472
The particulate properties of α-lactose monohydrate (αLMH), an excipient and carrier for pharmaceuticals, is important for the design, formulation and performance of a wide range of drug products. Here an...
2.
Badawy M, Murnane D, Lewis K, Morgan N
J Environ Sci Health B . 2024 Jun; 59(8):437-447. PMID: 38869424
Rigorous risk assessments for those exposed to pesticides are carried out to satisfy crop protection regulatory requirements. Non-dietary risk assessments involve estimating the amount of residue which can be transferred...
3.
Rajbanshi A, Hilton E, Dreiss C, Murnane D, Cook M
Macromol Rapid Commun . 2024 Feb; 45(10):e2300723. PMID: 38395416
Emulsions are complex. Dispersing two immiscible phases, thus expanding an interface, requires effort to achieve and the resultant dispersion is thermodynamically unstable, driving the system toward coalescence. Furthermore, physical instabilities,...
4.
Ma C, Nguyen T, Gajjar P, Styliari I, Hammond R, Withers P, et al.
Mol Pharm . 2023 Sep; 20(10):5019-5031. PMID: 37682633
Grid-based systematic search methods are used to investigate molecule-molecule, molecule-surface, and surface-surface contributions to interparticle interactions in order to identify the crystal faces that most strongly affect particle behavior during...
5.
Gajjar P, Styliari I, Legh-Land V, Bale H, Tordoff B, Withers P, et al.
Eur J Pharm Biopharm . 2023 Sep; 191:265-275. PMID: 37657613
Dry powder inhalers (DPI) are important for topical drug delivery to the lungs, but characterising the pre-aerosolised powder microstructure is a key initial step in understanding the post-aerosolised blend performance....
6.
Badawy M, Murnane D, Lewis K, Morgan N
J Environ Sci Health B . 2023 Aug; 58(8):555-564. PMID: 37563806
Pesticides are vital in meeting the challenge of feeding the rapidly increasing world population. However, it is crucial that they are used in a way that does not compromise the...
7.
Hoffman E, Urbano L, Martin A, Mahendran R, Patel A, Murnane D, et al.
Toxicol Appl Pharmacol . 2023 Jun; 474:116608. PMID: 37385476
One of the main hurdles in the development of new inhaled medicines is the frequent observation of foamy macrophage (FM) responses in non-clinical studies in experimental animals, which raises safety...
8.
Badawy M, Murnane D, Lewis K, Morgan N
Ann Work Expo Health . 2022 Jun; 66(8):1070-1080. PMID: 35765246
The dislodgeable foliar residue (DFR) is the amount of pesticide that exists on foliage after the pesticide has dried and which could dislodge to the skin or clothes of workers...
9.
Hoffman E, Napieralska P, Mahendran R, Murnane D, Hutter V
Front Immunol . 2021 Sep; 12:611280. PMID: 34539620
Introduction: Lung diseases are an increasing global health burden affecting millions of people worldwide. Only a few new inhaled medicines have reached the market in the last 30 years, in...
10.
Ahmad S, Baker D, Murnane D, Spooner N, Gerhard U
Bioanalysis . 2021 Jul; 13(14):1101-1111. PMID: 34275331
Determination of plasma protein binding () is considered vital for better understanding of pharmacokinetic and pharmacodynamic activities of drugs due to the role of free concentration in pharmacological response. Solid-phase...