Darko Markovic
Overview
Explore the profile of Darko Markovic including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
631
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0
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Recent Articles
1.
Triller P, Bachorz J, Synowitz M, Kettenmann H, Markovic D
Int J Mol Sci
. 2020 Apr;
21(8).
PMID: 32331440
Malignant gliomas are primary brain tumors with poor prognoses. These tumors are infiltrated by brain intrinsic microglia and peripheral monocytes which promote glioma cell invasion. In our previous studies, we...
2.
let-7 MicroRNAs Regulate Microglial Function and Suppress Glioma Growth through Toll-Like Receptor 7
Buonfiglioli A, Efe I, Guneykaya D, Ivanov A, Huang Y, Orlowski E, et al.
Cell Rep
. 2019 Dec;
29(11):3460-3471.e7.
PMID: 31825829
Microglia express Toll-like receptors (TLRs) that sense pathogen- and host-derived factors, including single-stranded RNA. In the brain, let-7 microRNA (miRNA) family members are abundantly expressed, and some have recently been...
3.
Szulzewsky F, Arora S, de Witte L, Ulas T, Markovic D, Schultze J, et al.
Glia
. 2016 Jun;
64(8):1416-36.
PMID: 27312099
Glioblastoma (GBM) is the most aggressive brain tumor in adults. It is strongly infiltrated by microglia and peripheral monocytes that support tumor growth. In the present study we used RNA...
4.
Szulzewsky F, Pelz A, Feng X, Synowitz M, Markovic D, Langmann T, et al.
PLoS One
. 2015 Feb;
10(2):e0116644.
PMID: 25658639
Malignant glioma belong to the most aggressive neoplasms in humans with no successful treatment available. Patients suffering from glioblastoma multiforme (GBM), the highest-grade glioma, have an average survival time of...
5.
Hu F, Ku M, Markovic D, Dzaye O, Lehnardt S, Synowitz M, et al.
Int J Cancer
. 2014 Apr;
135(11):2569-78.
PMID: 24752463
The invasiveness of malignant gliomas is one of the major obstacles in glioma therapy and the reason for the poor survival of patients. Glioma cells infiltrate into the brain parenchyma...
6.
Vinnakota K, Hu F, Ku M, Georgieva P, Szulzewsky F, Pohlmann A, et al.
Neuro Oncol
. 2013 Sep;
15(11):1457-68.
PMID: 24014382
Background: Glioblastomas are the most aggressive primary brain tumors in humans. Microglia/brain macrophage accumulation in and around the tumor correlates with malignancy and poor clinical prognosis of these tumors. We...
7.
Cuzic S, Bosnar M, Dominis Kramaric M, Ferencic Z, Markovic D, Glojnaric I, et al.
Toxicol Pathol
. 2012 Jun;
40(8):1169-87.
PMID: 22659244
Smoking-associated chronic obstructive pulmonary disease is characterized by inflammation, changes affecting small airways, and development of emphysema. Various short- and long-term models have been introduced to investigate these processes. The...
8.
Fucic A, Stojkovic R, Miskov S, Zeljezic D, Markovic D, Gjergja R, et al.
Reprod Toxicol
. 2010 Oct;
30(4):613-8.
PMID: 20955786
Antiepileptic drugs (AED) as transplacental agents are known to have adverse effects on fetal development. Genotoxicity of AEDs is still not fully understood. The aim of present study was to...
9.
Fucic A, Markovic D, Herceg Z, Gamulin M, Katic J, Stojkovic R, et al.
Mutat Res
. 2008 Sep;
657(1):43-7.
PMID: 18789400
Over the last 40 years mankind has been facing new types of radiochemical environmental settings with every decade. During the last decade, biomonitoring was additionally focused on assessing associations between...
10.
Sliwa M, Markovic D, Gabrusiewicz K, Synowitz M, Glass R, Zawadzka M, et al.
Brain
. 2006 Nov;
130(Pt 2):476-89.
PMID: 17107968
The invasion of tumour cells into brain tissue is a pathologic hallmark of WHO grades II-IV gliomas and contributes significantly to the failure of current therapeutic treatments. Activated microglial cells...