Darja Andreev
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Explore the profile of Darja Andreev including associated specialties, affiliations and a list of published articles.
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18
Citations
370
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Recent Articles
1.
Jia Y, Li R, Li Y, Kachler K, Meng X, Giessl A, et al.
Bone Res
. 2025 Jan;
13(1):9.
PMID: 39814705
Osteocytes are the main cells in mineralized bone tissue. Elevated osteocyte apoptosis has been observed in lytic bone lesions of patients with multiple myeloma. However, their precise contribution to bone...
2.
Kachler K, Andreev D, Thapa S, Royzman D, Giessl A, Karuppusamy S, et al.
Ann Rheum Dis
. 2024 Jul;
83(12):1691-1706.
PMID: 38964754
Objectives: Metabolic changes are crucially involved in osteoclast development and may contribute to bone degradation in rheumatoid arthritis (RA). The enzyme aconitate decarboxylase 1 (Acod1) is known to link the...
3.
Jia Y, Zhang F, Meng X, Andreev D, Lyu P, Zhang W, et al.
Cancer Lett
. 2024 Apr;
590:216866.
PMID: 38589005
Bone metastasis is a common complication of certain cancers such as melanoma. The spreading of cancer cells into the bone is supported by changes in the bone marrow environment. The...
4.
Andreev D, Kachler K, Liu M, Chen Z, Krishnacoumar B, Ringer M, et al.
Nat Commun
. 2024 Feb;
15(1):1067.
PMID: 38316791
Eosinophils are involved in tissue homeostasis. Herein, we unveiled eosinophils as important regulators of bone homeostasis. Eosinophils are localized in proximity to bone-resorbing osteoclasts in the bone marrow. The absence...
5.
Zhang W, Lyu P, Andreev D, Jia Y, Zhang F, Bozec A
Front Cell Dev Biol
. 2022 Dec;
10:974851.
PMID: 36578780
Increasing evidences have shown that hypoxia and the immune microenvironment play vital roles in the development of osteosarcoma. However, reliable gene signatures based on the combination of hypoxia and the...
6.
A new platform for autoimmune diseases. Inducing tolerance with liposomes encapsulating autoantigens
Almenara-Fuentes L, Rodriguez-Fernandez S, Rosell-Mases E, Kachler K, You A, Salvado M, et al.
Nanomedicine
. 2022 Dec;
48:102635.
PMID: 36481472
Autoimmune diseases (AIDs) are caused by the loss of self-tolerance and destruction of tissues by the host's immune system. Several antigen-specific immunotherapies, focused on arresting the autoimmune attack, have been...
7.
Royzman D, Andreev D, Stich L, Peckert-Maier K, Wild A, Zinser E, et al.
Front Immunol
. 2022 Aug;
13:936995.
PMID: 36003376
Here we show that soluble CD83 induces the resolution of inflammation in an antigen-induced arthritis (AIA) model. Joint swelling and the arthritis-related expression levels of IL-1β, IL-6, RANKL, MMP9, and...
8.
Wen J, Lyu P, Stolzer I, Xu J, Giessl A, Lin Z, et al.
Ann Rheum Dis
. 2022 Jun;
81(8):1119-1130.
PMID: 35710307
Objective: To investigate how the mucosal barrier in the intestine influences the development of arthritis, considering that metabolic changes in the intestinal epithelium influence its barrier function. Methods: Intestinal hypoxia...
9.
Andreev D, Kachler K, Schett G, Bozec A
Bone
. 2022 Jun;
162:116468.
PMID: 35688359
The term osteoimmunology describes an interdisciplinary research field that links the investigation of osteology (bone cells) with immunology. The crosstalk between innate and adaptive immune cells and cells involved in...
10.
Meng X, Lin Z, Cao S, Janowska I, Sonomoto K, Andreev D, et al.
Bone Res
. 2022 Feb;
10(1):15.
PMID: 35177582
In the bone marrow, B cells and bone-resorbing osteoclasts colocalize and form a specific microenvironment. How B cells functionally influence osteoclasts and bone architecture is poorly understood. Using genetically modified...