Dariusz Lachowski
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Explore the profile of Dariusz Lachowski including associated specialties, affiliations and a list of published articles.
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22
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Recent Articles
1.
Gomez-Cruz C, Fernandez-de la Torre M, Lachowski D, Prados-de-Haro M, Del Rio Hernandez A, Perea G, et al.
Adv Mater
. 2024 Apr;
36(26):e2312497.
PMID: 38610101
This work introduces NeoMag, a system designed to enhance cell mechanics assays in substrate deformation studies. NeoMag uses multidomain magneto-active materials to mechanically actuate the substrate, transmitting reversible mechanical cues...
2.
Yaganoglu S, Kalyviotis K, Vagena-Pantoula C, Julich D, Gaub B, Welling M, et al.
Nat Commun
. 2023 Sep;
14(1):5787.
PMID: 37723163
No abstract available.
3.
Yaganoglu S, Kalyviotis K, Vagena-Pantoula C, Julich D, Gaub B, Welling M, et al.
Nat Commun
. 2023 Jul;
14(1):4352.
PMID: 37468521
Mechanosensing is a ubiquitous process to translate external mechanical stimuli into biological responses. Piezo1 ion channels are directly gated by mechanical forces and play an essential role in cellular mechanotransduction....
4.
Matellan C, Lachowski D, Cortes E, Chiam K, Krstic A, Thorpe S, et al.
Oncogenesis
. 2023 May;
12(1):23.
PMID: 37130839
Pancreatic ductal adenocarcinoma (PDAC) is the most common and lethal form of pancreatic cancer, characterised by stromal remodelling, elevated matrix stiffness and high metastatic rate. Retinoids, compounds derived from vitamin...
5.
Blackford S, Yu T, Norman M, Syanda A, Manolakakis M, Lachowski D, et al.
Biomaterials
. 2023 Jan;
293:121982.
PMID: 36640555
Human pluripotent stem cell-derived hepatocytes (hPSC-Heps) may be suitable for treating liver diseases, but differentiation protocols often fail to yield adult-like cells. We hypothesised that replicating healthy liver niche biochemical...
6.
Mehta V, Pang K, Rozbesky D, Nather K, Keen A, Lachowski D, et al.
Nature
. 2022 May;
605(7910):E6.
PMID: 35504972
No abstract available.
7.
Lachowski D, Matellan C, Gopal S, Cortes E, Robinson B, Saiani A, et al.
ACS Nano
. 2022 Mar;
16(3):4322-4337.
PMID: 35255206
Liver fibrosis, a condition characterized by extensive deposition and cross-linking of extracellular matrix (ECM) proteins, is idiosyncratic in cases of chronic liver injury. The dysregulation of ECM remodeling by hepatic...
8.
Lachowski D, Matellan C, Cortes E, Saiani A, Miller A, Del Rio Hernandez A
Cancers (Basel)
. 2021 Jul;
13(13).
PMID: 34209094
The tumor microenvironment plays a critical role in modulating cancer cell migration, metabolism, and malignancy, thus, highlighting the need to develop in vitro culture systems that can recapitulate its abnormal...
9.
Lachowski D, Cortes E, Matellan C, Rice A, Lee D, Thorpe S, et al.
Front Cell Dev Biol
. 2020 Nov;
8:592628.
PMID: 33195261
Mechanical forces regulate cell functions through multiple pathways. G protein-coupled estrogen receptor (GPER) is a seven-transmembrane receptor that is ubiquitously expressed across tissues and mediates the acute cellular response to...
10.
Ghose R, Rice A, Cortes E, Ghose U, Lachowski D, Del Rio Hernandez A
Methods Cell Biol
. 2020 Apr;
157:99-122.
PMID: 32334722
Metastasis accounts for nearly 90% of all cancer associated mortalities. A hallmark of metastasis in malignancies of epithelial origin such as in the pancreas and breast, is invasion of the...