Dariusz Brzezinski
Overview
Explore the profile of Dariusz Brzezinski including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
21
Citations
161
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Karolczak J, Przybylowska A, Szewczyk K, Taisner W, Heumann J, Stowell M, et al.
Bioinformatics
. 2024 Dec;
41(1).
PMID: 39700427
Motivation: Accurately identifying ligands plays a crucial role in the process of structure-guided drug design. Based on density maps from X-ray diffraction or cryogenic-sample electron microscopy (cryoEM), scientists verify whether...
2.
Wlodawer A, Dauter Z, Rubach P, Minor W, Loch J, Brzezinski D, et al.
IUCrJ
. 2024 Oct;
11(Pt 6):966-976.
PMID: 39465564
The absence of solvent molecules in high-resolution protein crystal structure models deposited in the Protein Data Bank (PDB) contradicts the fact that, for proteins crystallized from aqueous media, water molecules...
3.
Karolczak J, Przybylowska A, Szewczyk K, Taisner W, Heumann J, Stowell M, et al.
bioRxiv
. 2024 Sep;
PMID: 39257821
Motivation: Accurately identifying ligands plays a crucial role in the process of structure-guided drug design. Based on density maps from X-ray diffraction or cryogenic-sample electron microscopy (cryoEM), scientists verify whether...
4.
Wlodawer A, Dauter Z, Lubkowski J, Loch J, Brzezinski D, Gilski M, et al.
Acta Crystallogr D Struct Biol
. 2024 Jun;
80(Pt 7):506-527.
PMID: 38935343
The Protein Data Bank (PDB) includes a carefully curated treasury of experimentally derived structural data on biological macromolecules and their various complexes. Such information is fundamental for a multitude of...
5.
Piernik M, Brzezinski D, Sztromwasser P, Pacewicz K, Majer-Burman W, Gniot M, et al.
Bioinformatics
. 2022 Aug;
38(19):4466-4473.
PMID: 35929780
Motivation: Whole-genome sequencing has revolutionized biosciences by providing tools for constructing complete DNA sequences of individuals. With entire genomes at hand, scientists can pinpoint DNA fragments responsible for oncogenesis and...
6.
Czyzewski A, Krawiec F, Brzezinski D, Porebski P, Minor W
Expert Syst Appl
. 2021 Aug;
174.
PMID: 34366575
Our understanding of life is based upon the interpretation of macromolecular structures and their dynamics. Almost 90% of currently known macromolecular models originated from electron density maps constructed using X-ray...
7.
Grabowski M, Macnar J, Cymborowski M, Cooper D, Shabalin I, Gilski M, et al.
IUCrJ
. 2021 May;
8(Pt 3):395-407.
PMID: 33953926
As part of the global mobilization to combat the present pandemic, almost 100 000 COVID-19-related papers have been published and nearly a thousand models of macromolecules encoded by SARS-CoV-2 have...
8.
Brzezinski D, Porebski P, Kowiel M, Macnar J, Minor W
Nucleic Acids Res
. 2021 Apr;
49(W1):W86-W92.
PMID: 33905501
Structure-guided drug design depends on the correct identification of ligands in crystal structures of protein complexes. However, the interpretation of the electron density maps is challenging and often burdened with...
9.
Jaskolski M, Dauter Z, Shabalin I, Gilski M, Brzezinski D, Kowiel M, et al.
IUCrJ
. 2021 Mar;
8(Pt 2):238-256.
PMID: 33708401
The appearance at the end of 2019 of the new SARS-CoV-2 coronavirus led to an unprecedented response by the structural biology community, resulting in the rapid determination of many hundreds...
10.
Grabowski M, Cooper D, Brzezinski D, Macnar J, Shabalin I, Cymborowski M, et al.
Nucl Instrum Methods Phys Res B
. 2021 Feb;
489:30-40.
PMID: 33603257
Intense X-rays available at powerful synchrotron beamlines provide macromolecular crystallographers with an incomparable tool for investigating biological phenomena on an atomic scale. The resulting insights into the mechanism's underlying biological...