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Daren Elkrief

Explore the profile of Daren Elkrief including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 81
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Recent Articles
1.
Elkrief D, Matusovsky O, Cheng Y, Rassier D
J Muscle Res Cell Motil . 2023 Oct; 44(4):225-254. PMID: 37805961
Actin-myosin interactions form the basis of the force-producing contraction cycle within the sarcomere, serving as the primary mechanism for muscle contraction. Post-translational modifications, such as oxidation, have a considerable impact...
2.
Elkrief D, Cheng Y, Matusovsky O, Rassier D
Am J Physiol Cell Physiol . 2022 Sep; 323(4):C1206-C1214. PMID: 36062880
The interaction between actin and myosin is the basis of contraction and force production in muscle fibers. Studies have shown that actin and myosin oxidation cause myofibrillar weakness in healthy...
3.
Kapchinsky S, Vuda M, Miguez K, Elkrief D, de Souza A, Baglole C, et al.
J Physiol . 2018 Apr; 596(14):2865-2881. PMID: 29663403
Key Points: Chronic obstructive pulmonary disease (COPD) is largely caused by smoking, and patient limb muscle exhibits a fast fibre shift and atrophy. We show that this fast fibre shift...
4.
Aare S, Spendiff S, Vuda M, Elkrief D, Perez A, Wu Q, et al.
Skelet Muscle . 2016 Sep; 6(1):29. PMID: 27588166
Background: Skeletal muscle displays a marked accumulation of denervated myofibers at advanced age, which coincides with an acceleration of muscle atrophy. Methods: In this study, we evaluated the hypothesis that...