Dara L Burdette
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Explore the profile of Dara L Burdette including associated specialties, affiliations and a list of published articles.
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14
Citations
2254
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Recent Articles
1.
Burdette D, Lazerwith S, Yang J, Chan H, Delaney Iv W, Fletcher S, et al.
PLoS One
. 2022 Apr;
17(4):e0262516.
PMID: 35363817
Nucleos(t)ide analogs are standard-of-care for the treatment of chronic hepatitis B and can effectively reduce hepatitis B virus (HBV) replication but rarely leads to cure. Nucleos(t)ide analogs do not directly...
2.
Holm C, Rahbek S, Gad H, Bak R, Jakobsen M, Jiang Z, et al.
Nat Commun
. 2016 Feb;
7:10680.
PMID: 26893169
Stimulator of interferon genes (STING) is known be involved in control of DNA viruses but has an unexplored role in control of RNA viruses. During infection with DNA viruses STING...
3.
Sreelatha A, Bennett T, Carpinone E, OBrien K, Jordan K, Burdette D, et al.
Proc Natl Acad Sci U S A
. 2014 Dec;
112(1):100-5.
PMID: 25453092
Vesicle fusion governs many important biological processes, and imbalances in the regulation of membrane fusion can lead to a variety of diseases such as diabetes and neurological disorders. Here we...
4.
Diner E, Burdette D, Wilson S, Monroe K, Kellenberger C, Hyodo M, et al.
Cell Rep
. 2013 May;
3(5):1355-61.
PMID: 23707065
The presence of foreign DNA in the cytosol of mammalian cells elicits a potent antiviral interferon response. Recently, cytosolic DNA was proposed to induce the synthesis of cyclic GMP-AMP (cGAMP)...
5.
Barker J, Koestler B, Carpenter V, Burdette D, Waters C, Vance R, et al.
mBio
. 2013 May;
4(3):e00018-13.
PMID: 23631912
Unlabelled: STING (stimulator of interferon [IFN] genes) initiates type I IFN responses in mammalian cells through the detection of microbial nucleic acids. The membrane-bound obligate intracellular bacterium Chlamydia trachomatis induces...
6.
Conlon J, Burdette D, Sharma S, Bhat N, Thompson M, Jiang Z, et al.
J Immunol
. 2013 Apr;
190(10):5216-25.
PMID: 23585680
Vascular disrupting agents such as 5,6-dimethylxanthenone-4-acetic acid (DMXAA) represent a novel approach for cancer treatment. DMXAA has potent antitumor activity in mice and, despite significant preclinical promise, failed human clinical...
7.
Burdette D, Vance R
Nat Immunol
. 2012 Dec;
14(1):19-26.
PMID: 23238760
Cytosolic detection of pathogen-derived nucleic acids is critical for the initiation of innate immune defense against diverse bacterial, viral and eukaryotic pathogens. Conversely, inappropriate responses to cytosolic nucleic acids can...
8.
Burdette D, Monroe K, Sotelo-Troha K, Iwig J, Eckert B, Hyodo M, et al.
Nature
. 2011 Sep;
478(7370):515-8.
PMID: 21947006
The innate immune system detects infection by using germline-encoded receptors that are specific for conserved microbial molecules. The recognition of microbial ligands leads to the production of cytokines, such as...
9.
Burdette D, Seemann J, Orth K
Mol Microbiol
. 2009 Jul;
73(4):639-49.
PMID: 19627496
Vibrio parahaemolyticus is a Gram-negative bacterium responsible for gastroenteritis acquired from the consumption of contaminated shellfish. This bacterium harbours two type III secretion systems, one on each chromosome. The type...
10.
Burdette D, Yarbrough M, Orth K
Autophagy
. 2008 Nov;
5(1):100-2.
PMID: 19011375
Vibrio parahaemolyticus (V. parahaemolyticus) is a gram-negative halophillic bacterium that causes worldwide seafood-borne gastroenteritis. The prevalence of V. parahaemolyticus in the environment and incidence of infection have been linked to...