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Danny C Alexander

Explore the profile of Danny C Alexander including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 1608
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Recent Articles
1.
Mayer J, Wone B, Alexander D, Guo L, Ryals J, Cushman J
Funct Plant Biol . 2021 Apr; 48(7):717-731. PMID: 33896444
Cactus pear (Opuntia ficus-indica) is a high productivity species within the Cactaceae grown in many semiarid parts of the world for food, fodder, forage, and biofuels. O. ficus-indica utilises obligate...
2.
Niehaus T, Patterson J, Alexander D, Folz J, Pyc M, MacTavish B, et al.
Biochem J . 2019 Jan; 476(4):683-697. PMID: 30692244
The tripeptide glutathione (GSH) is implicated in various crucial physiological processes including redox buffering and protection against heavy metal toxicity. GSH is abundant in plants, with reported intracellular concentrations typically...
3.
Wu H, Bogdanov M, Zhang Y, Sun K, Zhao S, Song A, et al.
Sci Rep . 2016 Jul; 6:29637. PMID: 27436223
Although Lands' cycle was discovered in 1958, its function and cellular regulation in membrane homeostasis under physiological and pathological conditions remain largely unknown. Nonbiased high throughput metabolomic profiling revealed that...
4.
Guo L, Milburn M, Ryals J, Lonergan S, Mitchell M, Wulff J, et al.
Proc Natl Acad Sci U S A . 2015 Aug; 112(35):E4901-10. PMID: 26283345
Precision medicine, taking account of human individuality in genes, environment, and lifestyle for early disease diagnosis and individualized therapy, has shown great promise to transform medical care. Nontargeted metabolomics, with...
5.
Tuttle J, Nah G, Duke M, Alexander D, Guan X, Song Q, et al.
BMC Genomics . 2015 Jun; 16:477. PMID: 26116072
Background: The morphogenesis of single-celled cotton fiber includes extreme elongation and staged cell wall differentiation. Designing strategies for improving cotton fiber for textiles and other uses relies on uncovering the...
6.
Coneva V, Simopoulos C, Casaretto J, El-Kereamy A, Guevara D, Cohn J, et al.
BMC Genomics . 2014 Dec; 15:1056. PMID: 25471115
Background: Understanding gene expression and metabolic re-programming that occur in response to limiting nitrogen (N) conditions in crop plants is crucial for the ongoing progress towards the development of varieties...
7.
Zhang Y, Berka V, Song A, Sun K, Wang W, Zhang W, et al.
J Clin Invest . 2014 May; 124(6):2750-61. PMID: 24837436
Sphingosine-1-phosphate (S1P) is a bioactive lipid that regulates multicellular functions through interactions with its receptors on cell surfaces. S1P is enriched and stored in erythrocytes; however, it is not clear...
8.
Clarke J, Alexander D, Ward D, Ryals J, Mitchell M, Wulff J, et al.
Sci Rep . 2013 Oct; 3:3082. PMID: 24170158
Genetically modified (GM) crops currently constitute a significant and growing part of agriculture.An important aspect of GM crop adoption is to demonstrate safety; identifying differences in end points with respect...
9.
Yamazaki M, Miyake M, Sato H, Masutomi N, Tsutsui N, Adam K, et al.
Toxicol Appl Pharmacol . 2013 Jan; 268(1):79-89. PMID: 23360887
Drug-induced liver injury (DILI) is a significant consideration for drug development. Current preclinical DILI assessment relying on histopathology and clinical chemistry has limitations in sensitivity and discordance with human. To...
10.
Yobi A, Wone B, Xu W, Alexander D, Guo L, Ryals J, et al.
Mol Plant . 2012 Dec; 6(2):369-85. PMID: 23239830
Selaginella lepidophylla is one of only a few species of spike mosses (Selaginellaceae) that have evolved desiccation tolerance (DT) or the ability to 'resurrect' from an air-dried state. In order...