Danny A Bitton
Overview
Explore the profile of Danny A Bitton including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
750
Followers
0
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Recent Articles
1.
Peter R, Hrobar P, Navratil J, Vagenknecht M, Soukup J, Tsuji K, et al.
Neuroinformatics
. 2024 Aug;
22(4):719-730.
PMID: 39107460
Annotation of multiple regions of interest across the whole mouse brain is an indispensable process for quantitative evaluation of a multitude of study endpoints in neuroscience digital pathology. Prior experience...
2.
Vostrosablin N, Lim S, Gopal P, Brazdilova K, Parajuli S, Wei X, et al.
NAR Genom Bioinform
. 2024 Mar;
6(1):lqae028.
PMID: 38482061
Recent COVID-19 vaccines unleashed the potential of mRNA-based therapeutics. A common bottleneck across mRNA-based therapeutic approaches is the rapid design of mRNA sequences that are translationally efficient, long-lived and non-immunogenic....
3.
Keeney J, Gulzar N, Baker J, Klempir O, Hannigan G, Bitton D, et al.
Drug Discov Today
. 2024 Jan;
29(3):103884.
PMID: 38219969
The volume of nucleic acid sequence data has exploded recently, amplifying the challenge of transforming data into meaningful information. Processing data can require an increasingly complex ecosystem of customized tools,...
4.
Waight A, Prihoda D, Shrestha R, Metcalf K, Bailly M, Ancona M, et al.
MAbs
. 2023 Aug;
15(1):2248671.
PMID: 37610144
Identification of favorable biophysical properties for protein therapeutics as part of developability assessment is a crucial part of the preclinical development process. Successful prediction of such properties and bioassay results...
5.
Brazdilova K, Prihoda D, Ton Q, Klock H, Bitton D
Bioinform Adv
. 2023 Jul;
3(1):vbad083.
PMID: 37456510
Motivation: Despite the advent of next-generation sequencing technology and its widespread applications, Sanger sequencing remains instrumental for molecular biology subcloning work in biological and medical research and indispensable for drug...
6.
Hoover A, Spale M, Lahue B, Bitton D
J Chem Inf Model
. 2023 Mar;
63(7):1852-1857.
PMID: 36977316
To solve recurring problems in drug discovery, matched molecular pair (MMP) analysis is used to understand relationships between chemical structure and function. For the MMP analysis of large data sets...
7.
Baylon J, Ursu O, Muzdalo A, Wassermann A, Adams G, Spale M, et al.
J Chem Inf Model
. 2022 Feb;
62(5):1259-1267.
PMID: 35192366
Therapeutic peptides offer potential advantages over small molecules in terms of selectivity, affinity, and their ability to target "undruggable" proteins that are associated with a wide range of pathologies. Despite...
8.
Prihoda D, Maamary J, Waight A, Juan V, Fayadat-Dilman L, Svozil D, et al.
MAbs
. 2022 Feb;
14(1):2020203.
PMID: 35133949
Despite recent advances in transgenic animal models and display technologies, humanization of mouse sequences remains one of the main routes for therapeutic antibody development. Traditionally, humanization is manual, laborious, and...
9.
Hiraga K, Mejzlik P, Marcisin M, Vostrosablin N, Gromek A, Arnold J, et al.
ACS Synth Biol
. 2021 Jan;
10(2):357-370.
PMID: 33433999
Protein engineering is the discipline of developing useful proteins for applications in research, therapeutic, and industrial processes by modification of naturally occurring proteins or by invention of proteins. Modern protein...
10.
Prihoda D, Maritz J, Klempir O, Dzamba D, Woelk C, Hazuda D, et al.
Nat Prod Rep
. 2020 Nov;
38(6):1100-1108.
PMID: 33245088
Covering: up to the end of 2020. The machine learning field can be defined as the study and application of algorithms that perform classification and prediction tasks through pattern recognition...