Danni A Gadd
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Explore the profile of Danni A Gadd including associated specialties, affiliations and a list of published articles.
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25
Citations
227
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Recent Articles
1.
Smith H, Ng H, Moodie J, Gadd D, McCartney D, Bernabeu E, et al.
Am J Hum Genet
. 2024 Dec;
112(1):106-115.
PMID: 39706196
Exploring the molecular correlates of metabolic health measures may identify their shared and unique biological processes and pathways. Molecular proxies of these traits may also provide a more objective approach...
2.
Gadd D, Smith H, Mullin D, Chybowska O, Hillary R, Kimenai D, et al.
Clin Epigenetics
. 2024 Sep;
16(1):124.
PMID: 39256775
Background: Plasma growth differentiation factor 15 (GDF15) and N-terminal proB-type natriuretic peptide (NT-proBNP) are cardiovascular biomarkers that associate with a range of diseases. Epigenetic scores (EpiScores) for GDF15 and NT-proBNP...
3.
Hillary R, Gadd D, Kuncheva Z, Mangelis T, Lin T, Ferber K, et al.
Nat Commun
. 2024 Aug;
15(1):7346.
PMID: 39187491
Understanding how gene-environment interactions (GEIs) influence the circulating proteome could aid in biomarker discovery and validation. The presence of GEIs can be inferred from single nucleotide polymorphisms that associate with...
4.
Gadd D, Hillary R, Kuncheva Z, Mangelis T, Cheng Y, Dissanayake M, et al.
Nat Aging
. 2024 Jul;
4(7):939-948.
PMID: 38987645
The circulating proteome offers insights into the biological pathways that underlie disease. Here, we test relationships between 1,468 Olink protein levels and the incidence of 23 age-related diseases and mortality...
5.
Mckinnon K, Conole E, Vaher K, Hillary R, Gadd D, Binkowska J, et al.
Clin Epigenetics
. 2024 Jul;
16(1):84.
PMID: 38951914
Background: Epigenetic scores (EpiScores), reflecting DNA methylation (DNAm)-based surrogates for complex traits, have been developed for multiple circulating proteins. EpiScores for pro-inflammatory proteins, such as C-reactive protein (DNAm CRP), are...
6.
Smith H, Ng H, Moodie J, Gadd D, McCartney D, Bernabeu E, et al.
medRxiv
. 2024 Jun;
PMID: 38853823
Exploring the molecular correlates of metabolic health measures may identify the shared and unique biological processes and pathways that they track. Here, we performed epigenome-wide association studies (EWASs) of six...
7.
Walker R, Chong M, Perrot N, Pigeyre M, Gadd D, Stolicyn A, et al.
Transl Psychiatry
. 2024 May;
14(1):204.
PMID: 38762535
Decline in cognitive function is the most feared aspect of ageing. Poorer midlife cognitive function is associated with increased dementia and stroke risk. The mechanisms underlying variation in cognitive function...
8.
Smith H, Moodie J, Monterrubio-Gomez K, Gadd D, Hillary R, Chybowska A, et al.
Clin Epigenetics
. 2024 Mar;
16(1):46.
PMID: 38528588
Background: Epigenetic Scores (EpiScores) for blood protein levels have been associated with disease outcomes and measures of brain health, highlighting their potential usefulness as clinical biomarkers. They are typically derived...
9.
Chybowska A, Gadd D, Cheng Y, Bernabeu E, Campbell A, Walker R, et al.
Circ Genom Precis Med
. 2024 Jan;
17(1):e004265.
PMID: 38288591
Background: Cardiovascular disease (CVD) is among the leading causes of death worldwide. The discovery of new omics biomarkers could help to improve risk stratification algorithms and expand our understanding of...
10.
Welsh P, Kimenai D, Shah A, Gadd D, Marioni R, Woodward M, et al.
Clin Chem
. 2023 Dec;
70(2):403-413.
PMID: 38069915
Background: Many studies have investigated whether single cardiac biomarkers improve cardiovascular risk prediction for primary prevention but whether a combined approach could further improve risk prediction is unclear. We aimed...