Dann L Parker
Overview
Explore the profile of Dann L Parker including associated specialties, affiliations and a list of published articles.
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4
Citations
42
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Recent Articles
1.
Buksh B, Knutson S, Oakley J, Bissonnette N, Oblinsky D, Schwoerer M, et al.
J Am Chem Soc
. 2022 Apr;
144(14):6154-6162.
PMID: 35363468
Modern proximity labeling techniques have enabled significant advances in understanding biomolecular interactions. However, current tools primarily utilize activation modes that are incompatible with complex biological environments, limiting our ability to...
2.
Guo L, Parker D, Zang Y, Sweis R, Liu W, Sherer E, et al.
ACS Med Chem Lett
. 2016 Dec;
7(12):1107-1111.
PMID: 27994747
GPR142 has been identified as a potential glucose-stimulated insulin secretion (GSIS) target for the treatment of type 2 diabetes mellitus (T2DM). A class of triazole GPR142 agonists was discovered through...
3.
Meng D, Andre P, Bateman T, Berger R, Chen Y, Desai K, et al.
Bioorg Med Chem Lett
. 2015 Aug;
25(22):5437-43.
PMID: 26318999
Using structure based drug design, a novel class of potent coagulation factor IXa (FIXa) inhibitors was designed and synthesized. High selectivity over FXa inhibition was achieved. Selected compounds were evaluated...
4.
Heasley B, Pacofsky G, Mamai A, Liu H, Nelson K, Coti G, et al.
Bioorg Med Chem Lett
. 2012 Jun;
22(22):6811-6.
PMID: 22672801
Orally bioavailable inhibitors of β-(1,3)-D-glucan synthase have been pursued as new, broad-spectrum fungicidal therapies suitable for treatment in immunocompromised patients. Toward this end, a collaborative medicinal chemistry program was established...