Daniil M Prigozhin
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Explore the profile of Daniil M Prigozhin including associated specialties, affiliations and a list of published articles.
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24
Citations
634
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Recent Articles
1.
Nikolopoulos N, Oda S, Prigozhin D, Modis Y
J Mol Biol
. 2024 Dec;
437(2):168890.
PMID: 39638237
The Human Silencing Hub (HUSH) guards the genome from the pathogenic effects of retroelement expression. Composed of MPP8, TASOR, and Periphilin-1, HUSH recognizes actively transcribed retrotransposed sequences by the presence...
2.
Prigozhin D, Sutherland C, Rangavajjhala S, Krasileva K
Mol Plant Microbe Interact
. 2024 Jul;
:MPMI05240047FI.
PMID: 39013614
Nucleotide-binding, leucine-rich repeat (LRR) proteins (NLRs) are a major class of immune receptors in plants. NLRs include both conserved and rapidly evolving members; however, their evolutionary trajectory in crops remains...
3.
Sutherland C, Prigozhin D, Monroe J, Krasileva K
EMBO Rep
. 2024 Mar;
25(5):2306-2322.
PMID: 38528170
Plants rely on Nucleotide-binding, Leucine-rich repeat Receptors (NLRs) for pathogen recognition. Highly variable NLRs (hvNLRs) show remarkable intraspecies diversity, while their low-variability paralogs (non-hvNLRs) are conserved between ecotypes. At a...
4.
Schopp T, Prigozhin D, Douse C, Kaji K, Cook A, OCarroll D
RNA
. 2023 Jul;
29(10):1471-1480.
PMID: 37433650
RNA-directed transposon silencing operates in the mammalian soma and germline to safeguard genomic integrity. The piRNA pathway and the HUSH complex identify active transposons through recognition of their nascent transcripts,...
5.
Caron V, Chassaing N, Ragge N, Boschann F, Ngu A, Meloche E, et al.
Genet Med
. 2023 Apr;
25(8):100856.
PMID: 37092537
Purpose: Dominant variants in the retinoic acid receptor beta (RARB) gene underlie a syndromic form of microphthalmia, known as MCOPS12, which is associated with other birth anomalies and global developmental...
6.
Sutherland C, Prigozhin D, Monroe J, Krasileva K
bioRxiv
. 2023 Jan;
PMID: 36711945
Plants rely on Nucleotide-binding, Leucine-rich repeat Receptors (NLRs) for pathogen recognition. Highly variable NLRs (hvNLRs) show remarkable intraspecies diversity, while their low variability paralogs (non-hvNLRs) are conserved between ecotypes. At...
7.
Regla-Nava J, Wang Y, Fontes-Garfias C, Liu Y, Syed T, Susantono M, et al.
Cell Rep
. 2022 Apr;
39(2):110655.
PMID: 35417697
Zika virus (ZIKV) and dengue virus (DENV) are arthropod-borne pathogenic flaviviruses that co-circulate in many countries. To understand some of the pressures that influence ZIKV evolution, we mimic the natural...
8.
Prigozhin D, Krasileva K
Plant Cell
. 2021 Feb;
33(4):998-1015.
PMID: 33561286
The evolution of recognition specificities by the immune system depends on the generation of receptor diversity and on connecting the binding of new antigens with the initiation of downstream signaling....
9.
Zhang Y, Prach L, OBrien T, DiMaio F, Prigozhin D, Corn J, et al.
Biochemistry
. 2020 Nov;
59(47):4507-4515.
PMID: 33182997
Terpenes make up the largest class of natural products, with extensive chemical and structural diversity. Diterpenes, mostly isolated from plants and rarely prokaryotes, exhibit a variety of important biological activities...
10.
Douse C, Tchasovnikarova I, Timms R, Protasio A, Seczynska M, Prigozhin D, et al.
Nat Commun
. 2020 Oct;
11(1):4940.
PMID: 33009411
The HUSH complex represses retroviruses, transposons and genes to maintain the integrity of vertebrate genomes. HUSH regulates deposition of the epigenetic mark H3K9me3, but how its three core subunits - ...