Danielle R Bruns
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Explore the profile of Danielle R Bruns including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
278
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Recent Articles
1.
Bettadapura S, Todd W, McGinnis G, Bruns D
J Mol Cell Cardiol
. 2025 Jan;
199:95-103.
PMID: 39753393
The age of the U.S. population is increasing alongside a growing burden of age-related cardiovascular disease. Circadian rhythms are critical for human health and are disrupted with aging and cardiovascular...
2.
Polson S, Thornburg J, McNair B, Cook C, Straight E, Fontana K, et al.
Can J Physiol Pharmacol
. 2024 Dec;
103(3):86-97.
PMID: 39693609
Diabetic cardiomyopathy (DCM) is a growing clinical entity and major health burden characterized by comorbid diabetes mellitus and heart failure. DCM has been commonly associated with impaired function of the...
3.
McNair B, Yusifov A, Thornburg J, Hoopes C, Satyanarayana S, Roy T, et al.
Aging Cell
. 2024 Sep;
24(1):e14339.
PMID: 39297345
Aging is the primary risk factor for heart disease, the leading global cause of death. Right ventricular (RV) function predicts survival in several age-related clinical contexts, yet no therapies directly...
4.
Shorthill S, Jones T, Woulfe K, Cherrington B, Bruns D
Can J Physiol Pharmacol
. 2024 Jan;
102(8):452-464.
PMID: 38266237
The lifetime risk of heart failure (HF) is comparable in men and women; nevertheless, disparities exist in our understanding of how HF differs between sexes. Several differences in cardiac physiology...
5.
OConnor A, Hatzenbiler D, Flom L, Bobadilla A, Bruns D, Schmitt E
Aerosp Med Hum Perform
. 2024 Jan;
94(12):887-893.
PMID: 38176033
High-altitude [>2400 m (7874 ft)] acclimatization has been well studied with physiological adaptations like reductions in body weight and exercise capacity. However, despite the significance of moderate altitude [MA, 1524-2438 ...
6.
Yusifov A, Borders M, DeHoff M, Polson S, Schmitt E, Bruns D
J Appl Physiol (1985)
. 2023 Jul;
135(3):572-583.
PMID: 37439235
Cardiovascular disease is an enormous public health problem, particularly in older populations. Exercise is the most potent cardioprotective intervention identified to date, with exercise in the juvenile period potentially imparting...
7.
McNair B, Polson S, Shorthill S, Yusifov A, Walker L, Weiser-Evans M, et al.
Am J Physiol Heart Circ Physiol
. 2023 Jun;
325(2):H278-H292.
PMID: 37389952
Right ventricular (RV) function is the strongest predictor of survival in age-related heart failure as well as other clinical contexts in which aging populations suffer significant morbidity and mortality. However,...
8.
McNair B, Shorthill S, Bruns D
Am J Physiol Heart Circ Physiol
. 2023 Jun;
325(2):H385-H397.
PMID: 37389951
Fibroblasts intricately organize and regulate the extracellular matrix (ECM) in cardiac health and disease. Excess deposition of ECM proteins causes fibrosis, resulting in disrupted signaling conduction and contributing to the...
9.
Bruns D, McNair B, Peelor 3rd F, Borowik A, Pranay A, Yusifov A, et al.
Geroscience
. 2023 Apr;
45(4):2545-2557.
PMID: 37118350
Right heart failure (RHF) is a common and deadly disease in aged populations. Extra-cardiac outcomes of RHF such as skeletal muscle atrophy contribute to morbidity and mortality. Despite the significance...
10.
Yusifova M, Yusifov A, Polson S, Todd W, Schmitt E, Bruns D
J Biol Rhythms
. 2023 Feb;
38(3):290-304.
PMID: 36802963
Circadian misalignment occurs with age, jet lag, and shift work, leading to maladaptive health outcomes including cardiovascular diseases. Despite the strong link between circadian disruption and heart disease, the cardiac...