Danielle L Sexton
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Explore the profile of Danielle L Sexton including associated specialties, affiliations and a list of published articles.
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12
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129
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Recent Articles
1.
Daher W, Le Moigne V, Tasrini Y, Parmar S, Sexton D, Aguilera-Correa J, et al.
Commun Biol
. 2025 Feb;
8(1):166.
PMID: 39900631
Type VII secretion systems participate in protein export, virulence, conjugation, and metabolic regulation. Five subtypes (ESX-1 to ESX-5) exist, each with specific roles and well-characterized secretion profiles in various mycobacterial...
2.
Sexton D, Hashimi A, Beskrovnaya P, Sibanda L, Huan T, Tocheva E
Proc Natl Acad Sci U S A
. 2023 Apr;
120(18):e2303275120.
PMID: 37094164
The presence of a cell membrane is one of the major structural components defining life. Recent phylogenomic analyses have supported the hypothesis that the last universal common ancestor (LUCA) was...
3.
Golmohammadzadeh M, Sexton D, Parmar S, Tocheva E
Adv Appl Microbiol
. 2023 Apr;
122:1-25.
PMID: 37085191
For decades, bacteria were thought of as "bags" of enzymes, lacking organelles and significant subcellular structures. This stood in sharp contrast with eukaryotes, where intracellular compartmentalization and the role of...
4.
von Kugelgen A, van Dorst S, Yamashita K, Sexton D, Tocheva E, Murshudov G, et al.
Proc Natl Acad Sci U S A
. 2023 Apr;
120(16):e2215808120.
PMID: 37043530
is an atypical diderm bacterium with a remarkable ability to tolerate various environmental stresses, due in part to its complex cell envelope encapsulated within a hyperstable surface layer (S-layer). Despite...
5.
Sexton D, Burgold S, Schertel A, Tocheva E
Curr Res Struct Biol
. 2022 Jan;
4:1-9.
PMID: 34977598
Studying bacterial cell envelope architecture with electron microscopy is challenging due to the poor preservation of microbial ultrastructure with traditional methods. Here, we established and validated a super-resolution cryo-correlative light...
6.
Sexton D, Chen G, Kara Murdoch F, Hashimi A, Loffler F, Tocheva E
Appl Environ Microbiol
. 2021 Nov;
88(2):e0190621.
PMID: 34788060
Dehalococcoides mccartyi () and spp. () are members of the class , phylum Chloroflexi, characterized by streamlined genomes and a strict requirement for organohalogens as electron acceptors. Here, we used...
7.
Beskrovnaya P, Sexton D, Golmohammadzadeh M, Hashimi A, Tocheva E
Front Microbiol
. 2021 Mar;
12:630573.
PMID: 33767680
Sporulation is a specialized developmental program employed by a diverse set of bacteria which culminates in the formation of dormant cells displaying increased resilience to stressors. This represents a major...
8.
Rens C, Chao J, Sexton D, Tocheva E, Av-Gay Y
Microbiology (Reading)
. 2021 Feb;
167(3).
PMID: 33629944
The success of as a pathogen is well established: tuberculosis is the leading cause of death by a single infectious agent worldwide. The threat of multi- and extensively drug-resistant bacteria...
9.
Sexton D, Tocheva E
Front Microbiol
. 2020 Oct;
11:581135.
PMID: 33072052
Many bacteria form spores in response to adverse environmental conditions. Several sporulation pathways have evolved independently and occur through distinctive mechanisms. Here, using cryo-electron tomography (cryo-ET), we examine all stages...
10.
Sexton D, Herlihey F, Brott A, Crisante D, Shepherdson E, Clarke A, et al.
J Biol Chem
. 2020 May;
295(27):9171-9182.
PMID: 32434927
Bacterial dormancy can take many forms, including formation of endospores, exospores, and metabolically latent cells. In the actinobacteria, including the streptomycetes and mycobacteria, the rapid resuscitation from a dormant state...