Danielle Fiechter
Overview
Explore the profile of Danielle Fiechter including associated specialties, affiliations and a list of published articles.
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10
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161
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Recent Articles
1.
Fiechter D, Kats S, Brands R, van Middelaar B, Pasterkamp G, de Kleijn D, et al.
Cardiol Res
. 2017 Mar;
2(5):236-242.
PMID: 28357012
Background: There has been increasing evidence suggesting that lipopolysaccharide or endotoxin may be an important activator of the innate immune system after acute myocardial infarction. Bovine intestinal alkaline phosphatase reduces...
2.
Kwast L, Aida T, Fiechter D, Kruijssen L, Bleumink R, Boon L, et al.
J Immunotoxicol
. 2016 Dec;
13(6):918-926.
PMID: 27967303
Immune-mediated drug hypersensitivity reactions (IDHR) may result from immuno-sensitization to a drug-induced neo-antigen. They rarely occur in patients and are usually not predicted preclinically using standard toxicity studies. To assess...
3.
Kwast L, Fiechter D, Kruijssen L, Bleumink R, Ludwig I, Bol-Schoenmakers M, et al.
J Immunotoxicol
. 2016 Apr;
13(4):535-47.
PMID: 27043250
The development of immune-dependent drug hypersensitivity reactions (IDHR) is likely to involve activation of the innate immune system to stimulate neo-antigen specific T-cells. Previously it has been shown that, upon...
4.
Jayasena S, Smits M, Fiechter D, de Jong A, Nordlee J, Baumert J, et al.
J Agric Food Chem
. 2015 Feb;
63(6):1849-55.
PMID: 25651402
Six commercial peanut enzyme-linked immunosorbent assay kits were assessed for their ability to recover peanut from the standard reference material 2387 peanut butter and also for their specificity in detecting...
5.
Schulz V, Smit J, Huijgen V, Bol-Schoenmakers M, van Roest M, Kruijssen L, et al.
Toxicol Sci
. 2012 Apr;
128(1):92-102.
PMID: 22491429
Recently, we have shown that AhR activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) suppresses sensitization to peanut at least in part by inducing a functional shift toward CD4(+)CD25(+)Foxp3(+) T cells. Next to TCDD,...
6.
Smit J, Willemsen K, Hassing I, Fiechter D, Storm G, van Bloois L, et al.
PLoS One
. 2011 Dec;
6(12):e28917.
PMID: 22194949
Food allergy affects approximately 5% of children and is the leading cause of hospitalization for anaphylactic reactions in westernized countries. However, the pathways of anaphylaxis in food allergy are still...
7.
Kwast L, Fiechter D, Hassing I, Bleumink R, Boon L, Ludwig I, et al.
Toxicol Sci
. 2011 Mar;
121(2):312-9.
PMID: 21402728
Immune-mediated drug hypersensitivity reactions are important causes of black box warnings and drug withdrawals. Despite the high demand for preclinical screening tools, no validated in vitro or in vivo models...
8.
Bol-Schoenmakers M, Fiechter D, Raaben W, Hassing I, Bleumink R, Kruijswijk D, et al.
Eur J Pharmacol
. 2010 Feb;
633(1-3):71-7.
PMID: 20132812
Inflammatory bowel disease is characterized by chronic inflammation of the intestine and is accompanied by damage of the epithelial lining and by undesired immune responses towards enteric bacteria. It has...
9.
Ludwig I, Kwast L, Fiechter D, Pieters R
Methods Mol Biol
. 2009 Dec;
598:27-37.
PMID: 19967504
New chemical entities are tested in general toxicity assays during development before entering clinical trials. However, immunosensitization of these entities is not tested on a standard basis. There are no...
10.
Beumer C, Wulferink M, Raaben W, Fiechter D, Brands R, Seinen W
J Pharmacol Exp Ther
. 2003 Sep;
307(2):737-44.
PMID: 12970380
It has been demonstrated that human placental alkaline phosphatase (HPLAP) attenuates the lipopolysaccharide (LPS)-mediated inflammatory response, likely through dephosphorylation of the lipid A moiety of LPS. In this study, it...