Danielle E Read
Overview
Explore the profile of Danielle E Read including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
241
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0
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Recent Articles
1.
Read D, Gupta A, Cawley K, Fontana L, Agostinis P, Samali A, et al.
Life (Basel)
. 2021 Jan;
11(1).
PMID: 33418948
An important event in the unfolded protein response (UPR) is activation of the endoplasmic reticulum (ER) kinase PERK. The PERK signalling branch initially mediates a prosurvival response, which progresses to...
2.
Gupta A, Hossain M, Read D, Hetz C, Samali A, Gupta S
Sci Rep
. 2015 Dec;
5:18304.
PMID: 26674075
The endoplasmic reticulum (ER) responds to changes in intracellular homeostasis through activation of the unfolded protein response (UPR). UPR can facilitate the restoration of cellular homeostasis, via the concerted activation...
3.
Gupta A, Read D, Gupta S
Methods Mol Biol
. 2015 Mar;
1292:19-38.
PMID: 25804745
The endoplasmic reticulum (ER) is responsible for the proper folding and processing of secreted and transmembrane proteins within the cell. Stimuli that disrupt ER function cause an accumulation of misfolded...
4.
Read D, Gupta A, Ladilov Y, Samali A, Gupta S
Cell Biosci
. 2014 Oct;
4(1):56.
PMID: 25302112
Background: Glucose and oxygen deprivation during ischemia is known to affect the homeostasis of the endoplasmic reticulum (ER) in ways predicted to activate the unfolded protein response (UPR). Activation of...
5.
Molloy N, Read D, Gorman A
Cancers (Basel)
. 2013 Nov;
3(1):510-30.
PMID: 24212627
One of the major challenges for cancer therapeutics is the resistance of many tumor cells to induction of cell death due to pro-survival signaling in the cancer cells. Here we...
6.
Read D, Gorman A
Cell Mol Life Sci
. 2009 Jun;
66(18):2975-84.
PMID: 19504044
The regulation of neuronal differentiation and neurite outgrowth is essential during development of the nervous system and is crucial in developing therapies to promote axon regeneration after nerve injury or...
7.
Read D, Gorman A
Biochem Biophys Res Commun
. 2009 Mar;
382(1):6-8.
PMID: 19249290
The small heat shock protein 27 (Hsp27) is well documented to promote neuronal survival in neurodegenerative diseases and following nerve injury. It can directly inhibit apoptotic pathways, and as a...
8.
Read D, Reed Herbert K, Gorman A
Brain Res
. 2008 Jun;
1221:14-23.
PMID: 18561899
Neuronal differentiation and neurite outgrowth are key processes during development of the nervous system. Understanding the regulation of neurite outgrowth stimulated by neurotrophins is crucial to developing therapies to promote...