Danielle E Mor
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Explore the profile of Danielle E Mor including associated specialties, affiliations and a list of published articles.
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15
Citations
403
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Recent Articles
1.
Cisterna B, Skruber K, Jane M, Camesi C, Nguyen I, Liu T, et al.
J Cell Biol
. 2024 May;
223(7).
PMID: 38722279
In addition to its well-established role in actin assembly, profilin 1 (PFN1) has been shown to bind to tubulin and alter microtubule growth. However, whether PFN1's predominant control over microtubules...
2.
Mor D
Trends Biochem Sci
. 2024 Mar;
49(5):382-383.
PMID: 38453543
Phosphorylation of α-synuclein protein at serine-129 (Ser129P) is a widely used marker for disease pathology in neurodegenerative disorders termed synucleinopathies. In groundbreaking work by Parra-Rivas, Madhivanan et al., Ser129P was...
3.
Chen M, Mor D
Int J Mol Sci
. 2023 Apr;
24(8).
PMID: 37108366
Parkinson's disease (PD) is a multifactorial disorder involving both motor and non-motor symptoms caused by the progressive death of distinct neuronal populations, including dopaminergic neurons in the substantia nigra. The...
4.
Chen M, Vincent J, Ezeanii A, Wakade S, Yerigenahally S, Mor D
Life Sci Alliance
. 2022 Jul;
5(11).
PMID: 35790300
Parkinson's disease (PD) is a debilitating neurodegenerative disorder characterized by progressive motor decline and the aggregation of α-synuclein protein. Growing evidence suggests that α-synuclein aggregates may spread from neurons of...
5.
McIntyre L, Huertas F, Morse A, Kaletsky R, Murphy C, Kalia V, et al.
Sci Rep
. 2022 Mar;
12(1):3268.
PMID: 35228596
Parkinson's disease (PD) is a disabling neurodegenerative disorder in which multiple cell types, including dopaminergic and cholinergic neurons, are affected. The mechanisms of neurodegeneration in PD are not fully understood,...
6.
Sohrabi S, Mor D, Kaletsky R, Keyes W, Murphy C
Commun Biol
. 2021 Feb;
4(1):203.
PMID: 33589689
We recently linked branched-chain amino acid transferase 1 (BCAT1) dysfunction with the movement disorder Parkinson's disease (PD), and found that RNAi-mediated knockdown of neuronal bcat-1 in C. elegans causes abnormal...
7.
Mor D, Murphy C
Transl Med Aging
. 2020 Nov;
4:117-120.
PMID: 33178902
Mitochondrial dysfunction is thought to contribute to neurodegeneration in Parkinson's disease (PD), yet the cellular events that lead to mitochondrial disruption remain unclear. Post-mortem studies of PD patient brains and...
8.
Mor D, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, et al.
Proc Natl Acad Sci U S A
. 2020 Oct;
117(42):26438-26447.
PMID: 33024014
Metabolic dysfunction occurs in many age-related neurodegenerative diseases, yet its role in disease etiology remains poorly understood. We recently discovered a potential causal link between the branched-chain amino acid transferase...
9.
Mor D, Daniels M, Ischiropoulos H
Mov Disord
. 2019 Jan;
34(2):167-179.
PMID: 30633814
Parkinson's disease (PD) is primarily a movement disorder driven by the loss of dopamine-producing neurons in the substantia nigra (SN). Early identification of the oxidative properties of dopamine implicated it...
10.
Yao V, Kaletsky R, Keyes W, Mor D, Wong A, Sohrabi S, et al.
Nat Biotechnol
. 2018 Oct;
PMID: 30346941
Effective discovery of causal disease genes must overcome the statistical challenges of quantitative genetics studies and the practical limitations of human biology experiments. Here we developed diseaseQUEST, an integrative approach...