Daniele Spehner
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Explore the profile of Daniele Spehner including associated specialties, affiliations and a list of published articles.
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30
Citations
558
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Recent Articles
1.
Franchet A, Haller S, Yamba M, Barbier V, Thomaz-Vieira A, Leclerc V, et al.
bioRxiv
. 2025 Feb;
PMID: 39975242
The digestive tract represents the most complex interface of an organism with its biotope. Food may be contaminated by pathogens and toxicants while an abundant and complex microbiota strives in...
2.
Girard J, Le Bihan O, Lai-Kee-Him J, Girleanu M, Bernard E, Castellarin C, et al.
J Virol
. 2024 Jun;
98(7):e0036824.
PMID: 38940586
Chikungunya virus (CHIKV) is a mosquito-borne pathogen responsible for an acute musculoskeletal disease in humans. Replication of the viral RNA genome occurs in specialized membranous replication organelles (ROs) or spherules,...
3.
Groysbeck N, Hanss V, Donzeau M, Strub J, Cianferani S, Spehner D, et al.
Small Methods
. 2023 Apr;
7(6):e2300098.
PMID: 37035956
Advances in cryo-electron microscopy (EM) enable imaging of protein assemblies within mammalian cells in a near native state when samples are preserved by cryogenic vitrification. To accompany this progress, specialized...
4.
Spehner D, Perino J, Crancec J, Favier A
Virologie (Montrouge)
. 2022 Sep;
15(4):279-280.
PMID: 36151676
No abstract available.
5.
Darouich O, Baaziz W, Ihiawakrim D, Hirlimann C, Spehner D, Schultz P, et al.
Nanoscale Adv
. 2022 Sep;
4(6):1587-1598.
PMID: 36134372
A full 3D analysis of the hierarchical porosity in sp. diatom structures was carried out by using a multiscale approach that combines three advanced volumetric imaging techniques with resolutions and...
6.
Groysbeck N, Donzeau M, Stoessel A, Haeberle A, Ory S, Spehner D, et al.
Nanoscale Adv
. 2022 Sep;
3(24):6940-6948.
PMID: 36132366
Advances in microscopy technology have prompted efforts to improve the reagents required to recognize specific molecules within the intracellular environment. For high-resolution electron microscopy, conjugation of selective binders originating from...
7.
Spehner D, Steyer A, Bertinetti L, Orlov I, Benoit L, Pernet-Gallay K, et al.
J Struct Biol
. 2020 May;
211(1):107528.
PMID: 32387573
Focused Ion Beam-Scanning Electron Microscopy (FIB-SEM) is an invaluable tool to visualize the 3D architecture of cell constituents and map cell networks. Recently, amorphous ice embedding techniques have been associated...
8.
Di Mattia T, Wilhelm L, Ikhlef S, Wendling C, Spehner D, Nomine Y, et al.
EMBO Rep
. 2018 Jun;
19(7).
PMID: 29858488
Membrane contact sites are cellular structures that mediate interorganelle exchange and communication. The two major tether proteins of the endoplasmic reticulum (ER), VAP-A and VAP-B, interact with proteins from other...
9.
Bonnard D, Le Rouzic E, Eiler S, Amadori C, Orlov I, Bruneau J, et al.
J Biol Chem
. 2018 Mar;
293(16):6172-6186.
PMID: 29507092
Recently, a new class of HIV-1 integrase (IN) inhibitors with a dual mode of action, called IN-LEDGF/p75 allosteric inhibitors (INLAIs), was described. Designed to interfere with the IN-LEDGF/p75 interaction during...
10.
Orlov I, Drillien R, Spehner D, Bergoin M, Abd-Alla A, Klaholz B
Virology
. 2017 Dec;
514:165-169.
PMID: 29190455
Glossina palipides salivary gland hypertrophy virus (GpSGHV) infects tsetse flies, which are vectors for African trypanosomosis. This virus represents a major challenge in insect mass rearing and has hampered the...