Daniela Miglietta
Overview
Explore the profile of Daniela Miglietta including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
146
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0
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Recent Articles
1.
Govoni M, Bassi M, Girardello L, Lucci G, Rony F, Charretier R, et al.
Respir Res
. 2024 Oct;
25(1):380.
PMID: 39427187
Background: Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory condition. Given patients with COPD continue to experience exacerbations despite the availability of effective therapies, anti-inflammatory treatments targeting novel pathways...
2.
Fioni A, Brogin G, Puccini P, Allen A, Miglietta D, Cuoghi E, et al.
J Aerosol Med Pulm Drug Deliv
. 2024 Sep;
38(1):18-25.
PMID: 39324250
A fixed combination of formoterol, glycopyrrolate, and beclomethasone dipropionate is approved in some geographic areas as pressurized metered dose inhaler (pMDI) formulation for the treatment of asthma and chronic obstructive...
3.
Carzaniga L, Linney I, Rizzi A, Schmidt W, Knight C, Mileo V, et al.
J Med Chem
. 2024 Jun;
67(12):9816-9841.
PMID: 38857426
Clinical guidelines for COPD and asthma recommend inhaled β-adrenergic agonists, muscarinic antagonists, and, for frequent exacerbators, inhaled corticosteroids, with the challenge of combining them into a single device. The MABA...
4.
Murgo A, Bignami F, Federico G, Villetti G, Civelli M, Sala A, et al.
Front Pharmacol
. 2023 Dec;
14:1303646.
PMID: 38099140
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, age-related interstitial lung disease (ILD) with limited therapeutic options. Despite the wide variety of different models for IPF, these preclinical models have...
5.
Carzaniga L, Linney I, Rizzi A, Delcanale M, Schmidt W, Knight C, et al.
J Med Chem
. 2022 Jul;
65(15):10233-10250.
PMID: 35901125
The development of molecules embedding two distinct pharmacophores acting as muscarinic antagonists and β agonists (MABAs) promises to be an excellent opportunity to reduce formulation issues and boost efficacy through...
6.
Oriano M, Terranova L, Sotgiu G, Saderi L, Bellofiore A, Retucci M, et al.
Pulm Pharmacol Ther
. 2019 Oct;
59:101856.
PMID: 31626976
Neutrophil elastase (NE) is a crucial marker of neutrophilic inflammation. We aimed to compare different techniques to detect active NE in sputum samples of 50 Bronchiectasis (BE) and 50 Cystic...
7.
Gramegna A, Amati F, Terranova L, Sotgiu G, Tarsia P, Miglietta D, et al.
Respir Res
. 2017 Dec;
18(1):211.
PMID: 29258516
The role of neutrophil elastase (NE) is poorly understood in bronchiectasis because of the lack of preclinical data and so most of the assumptions made about NE inhibitor potential benefit...
8.
Ripamonti C, Papagna A, Storini C, Miglietta D, Foti M
J Leukoc Biol
. 2017 Oct;
102(6):1421-1430.
PMID: 29021366
NO mediates a variety of physiologic processes and is considered an important intracellular messenger in different cellular systems. Because of its complex regulation and multiple molecular and cellular targets, NO...
9.
Miglietta D, De Palma C, Sciorati C, Vergani B, Pisa V, Villa A, et al.
Orphanet J Rare Dis
. 2015 Aug;
10:101.
PMID: 26296873
Background: In dystrophin-deficient muscles of Duchenne Muscular Dystrophy (DMD) patients and the mdx mouse model, nitric oxide (NO) signalling is impaired. Previous studies have shown that NO-donating drugs are beneficial...
10.
Amoruso A, Fresu L, Dalli J, Miglietta D, Bardelli C, Federici Canova D, et al.
Life Sci
. 2015 Feb;
126:28-36.
PMID: 25711428
Aims: Cyclooxygenase (COX)-inhibiting nitric oxide donors (CINODs) are a new class of drugs that structurally combine a COX inhibitor with a nitric oxide (NO) donating moiety. This combination reduces potential...