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Daniela Amaral Silva

Explore the profile of Daniela Amaral Silva including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 49
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Recent Articles
1.
Malavia N, Bao Q, Silva D, Wang Y, Alam K, Lukacova V, et al.
Int J Pharm . 2025 Feb; 673:125390. PMID: 40010523
Long-acting injectable (LAI) suspensions are controlled drug delivery systems that provide sustained drug release over durations ranging from one to six months. Although it is recognized that the particle agglomeration...
2.
Gong Y, Hopefl R, Li T, Hooker A, Silva D, Alam K, et al.
Pharm Res . 2025 Feb; PMID: 39939560
No abstract available.
3.
Gong Y, Hopefl R, Li T, Hooker A, Silva D, Alam K, et al.
Pharm Res . 2025 Jan; PMID: 39875758
The U.S. Food and Drug Administration (FDA) and the Center for Research on Complex Generics (CRCG) hosted a public workshop on May 2-3, 2024, titled "Considerations and Potential Regulatory Applications...
4.
Silva D, Le Merdy M, Alam K, Wang Y, Bao Q, Malavia N, et al.
Pharmaceutics . 2024 Apr; 16(4). PMID: 38675213
Long-acting injectable (LAI) formulations provide sustained drug release over an extended period ranging from weeks to several months to improve efficacy, safety, and compliance. Nevertheless, many challenges arise in the...
5.
Hajjar B, Zuo J, Park C, Azarmi S, Silva D, Bou-Chacra N, et al.
AAPS PharmSciTech . 2022 Apr; 23(4):102. PMID: 35378669
Topical microemulsion (ME) might provide a novel and advanced transdermal delivery system due to the enhances of drug solubility and permeability across the stratum corneum. Foams are topical delivery systems...
6.
Silva D, Davanco M, Davies N, Kramer J, de Oliveira Carvalho P, Lobenberg R
Int J Pharm . 2021 Jul; 605:120857. PMID: 34229072
There are many hurdles in the development of generic formulations. In vitro biopredictive dissolution conditions together with alternative in vitro - in vivo relationship (IVIVR) approaches can be a powerful...
7.
Silva D, Davies N, Doschak M, Al-Gousous J, Bou-Chacra N, Lobenberg R
J Control Release . 2020 Jul; 325:323-334. PMID: 32649973
Over the last 70 years several cases of in vivo failure of enteric coated (EC) formulations have been reported. The observed failures seem to be due to the slower than...
8.
Silva D, Pate D, Clark R, Davies N, El-Kadi A, Lobenberg R
Pharmacol Ther . 2020 Jul; 215:107621. PMID: 32615127
Cannabis is a plant with a long history of human pharmacological use, both for recreational purposes and as a medicinal remedy. Many potential modern medical applications for cannabis have been...
9.
Silva D, Al-Gousous J, Davies N, Chacra N, Webster G, Lipka E, et al.
Pharmaceutics . 2020 May; 12(5). PMID: 32370237
Dissolution testing is a major tool used to assess a drug product's performance and as a quality control test for solid oral dosage forms. However, compendial equipment and methods may...
10.
Njoku J, Silva D, Mukherjee D, Webster G, Lobenberg R
AAPS PharmSciTech . 2019 Jul; 20(6):243. PMID: 31264126
In early drug development, the selection of a formulation platform and decisions on formulation strategies have to be made within a short timeframe and often with minimal use of the...