Daniel Y Hung
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Explore the profile of Daniel Y Hung including associated specialties, affiliations and a list of published articles.
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12
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121
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Recent Articles
1.
Tom M, Li J, Ueno A, Fort Gasia M, Chan R, Hung D, et al.
Inflamm Bowel Dis
. 2016 Jun;
22(7):1596-608.
PMID: 27306067
Background: Distinct CD8+ T-cell subsets such as interleukin-17-expressing Tc17 and Foxp3-expressing Tcreg are functionally similar to CD4+ T cells. Though CD4+ T cells are dysregulated in patients with inflammatory bowel...
2.
Weiss M, Hung D, Poenicke K, Roberts M
Eur J Pharm Sci
. 2008 Jun;
34(4-5):345-50.
PMID: 18573335
Although the organic anion transporter Oatp2 plays a critical role in determining the hepatic clearance of some drugs, little quantitative information exists about its functional characteristics in relation to inhibition...
3.
Hunt C, Ropella G, Yan L, Hung D, Roberts M
J Pharmacokinet Pharmacodyn
. 2006 Oct;
33(6):737-72.
PMID: 17051440
Current physiologically based pharmacokinetic (PBPK) models are inductive. We present an additional, different approach that is based on the synthetic rather than the inductive approach to modeling and simulation. It...
4.
Hung D, Siebert G, Chang P, Whitehouse M, Fletcher L, Crawford D, et al.
Am J Physiol Gastrointest Liver Physiol
. 2005 Sep;
290(2):G343-51.
PMID: 16166348
Systemic inflammation is known to affect drug disposition in the liver. This study sought to relate and quantitate changes in hepatic pharmacokinetics of propranolol with changes in hepatic architecture and...
5.
Chang P, Hung D, Siebert G, Bridle K, Roberts M
Dig Dis Sci
. 2005 Apr;
50(4):745-52.
PMID: 15844712
The effects of a Chinese snake venom preparation from Agkistrodon halys pallas, used for treatment of hepatic fibrosis/cirrhosis in China, was investigated in an in vivo rat model and using...
6.
Hung D, Siebert G, Chang P, Roberts M
Br J Pharmacol
. 2005 Feb;
145(1):57-65.
PMID: 15711588
The disposition kinetics of [3H]taurocholate ([3H]TC) in perfused normal and cholestatic rat livers were studied using the multiple indicator dilution technique and several physiologically based pharmacokinetic models. The serum biochemistry...
7.
Hung D, Siebert G, Chang P, Burczynski F, Roberts M
Am J Physiol Gastrointest Liver Physiol
. 2004 Sep;
288(1):G93-100.
PMID: 15345470
Nonalcoholic fatty liver disease is the most common of all liver diseases. The hepatic disposition [(3)H]palmitate and its low-molecular-weight metabolites in perfused normal and steatotic rat liver were studied using...
8.
Hung D, Siebert G, Chang P, Anissimov Y, Roberts M
J Pharmacol Exp Ther
. 2004 Jun;
311(2):822-9.
PMID: 15192084
The aim of this study was to define the determinants of the linear hepatic disposition kinetics of propranolol optical isomers using a perfused rat liver. Monensin was used to abolish...
9.
Siebert G, Hung D, Chang P, Roberts M
J Pharmacol Exp Ther
. 2003 Oct;
308(1):228-35.
PMID: 14566005
This study investigated the relative contribution of ion-trapping, microsomal binding, and distribution of unbound drug as determinants in the hepatic retention of basic drugs in the isolated perfused rat liver....
10.
Hung D, Burczynski F, Chang P, Lewis A, Masci P, Siebert G, et al.
Am J Physiol Gastrointest Liver Physiol
. 2002 Nov;
284(3):G423-33.
PMID: 12444013
Disposition kinetics of [(3)H]palmitate and its low-molecular-weight metabolites in perfused rat livers were studied using the multiple-indicator dilution technique, a selective assay for [(3)H]palmitate and its low-molecular-weight metabolites, and several...