Daniel Vyoral
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Explore the profile of Daniel Vyoral including associated specialties, affiliations and a list of published articles.
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22
Citations
405
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Recent Articles
1.
Hrdinova T, Toman O, Dresler J, Klimentova J, Salovska B, Pajer P, et al.
Int J Oncol
. 2021 Jan;
58(2):238-250.
PMID: 33491750
Chronic myeloid leukemia (CML) is a malignant hematopoietic disorder distinguished by the presence of a BCR‑ABL1 fused oncogene with constitutive kinase activity. Targeted CML therapy by specific tyrosine kinase inhibitors...
2.
Scheiber I, Pilatova J, Malych R, Kotabova E, Krijt M, Vyoral D, et al.
Metallomics
. 2019 Aug;
11(10):1657-1666.
PMID: 31380866
Iron and copper are essential elements for practically all living organisms. Their metabolism is frequently interconnected, and while copper is relatively abundant in the ocean, iron is often a limiting...
3.
Petrak J, Havlenova T, Krijt M, Behounek M, Franekova J, Cervenka L, et al.
Biochim Biophys Acta Gen Subj
. 2019 Jan;
1863(4):703-713.
PMID: 30677469
Background: Up to 50% of patients with chronic heart failure (HF) have systemic iron deficiency, which contributes to symptoms and poor prognosis. Myocardial iron deficiency (MID) in HF patients has...
4.
Vyoral D, Petrak J
Pharmacol Res
. 2016 Nov;
115:242-254.
PMID: 27867027
Iron is an essential biogenic element for both prokaryotic and eukaryotic cells. In humans iron is present in hundreds of different metalloproteins. The peptide hormone hepcidin serves as a master...
5.
Huang M, Austin C, Sari M, Suryo Rahmanto Y, Ponka P, Vyoral D, et al.
J Biol Chem
. 2013 Jul;
288(35):25450-25465.
PMID: 23846698
Hepcidin regulates iron metabolism by down-regulating ferroportin-1 (Fpn1). We demonstrated that hepcidin is complexed to the blood transport protein, α2-macroglobulin (α2M) (Peslova, G., Petrak, J., Kuzelova, K., Hrdy, I., Halada,...
6.
Sillerova T, Zivny J, Vyoral D, Petrak J
Br J Nutr
. 2012 Feb;
108(10):1723-5.
PMID: 22321247
The peptide hormone hepcidin functions as a negative regulator of intestinal Fe absorption and Fe recycling. Since its discovery as a systemic negative regulator of Fe metabolism, hepcidin has attracted...
7.
cmejla R, Ptackova P, Petrak J, Savvulidi F, cerny J, Sebesta O, et al.
Biochem Biophys Res Commun
. 2010 Mar;
395(2):163-7.
PMID: 20188707
Myotonic dystrophy kinase-related Cdc42-binding kinase alpha (MRCKalpha, formally known as CDC42BPA) is a serine/threonine kinase that can regulate actin/myosin assembly and activity. Recently, it has been shown that it possesses...
8.
Peslova G, Petrak J, Kuzelova K, Hrdy I, Halada P, Kuchel P, et al.
Blood
. 2009 Apr;
113(24):6225-36.
PMID: 19380872
Hepcidin is a major regulator of iron metabolism. Hepcidin-based therapeutics/diagnostics could play roles in hematology in the future, and thus, hepcidin transport is crucial to understand. In this study, we...
9.
Singh A, Mohan M, Isaac A, Luo X, Petrak J, Vyoral D, et al.
PLoS One
. 2009 Feb;
4(2):e4468.
PMID: 19212444
Converging evidence leaves little doubt that a change in the conformation of prion protein (PrP(C)) from a mainly alpha-helical to a beta-sheet rich PrP-scrapie (PrP(Sc)) form is the main event...
10.
Petrak J, Ivanek R, Toman O, cmejla R, cmejlova J, Vyoral D, et al.
Proteomics
. 2008 Apr;
8(9):1744-9.
PMID: 18442176
After reading many 2-DE-based articles featuring lists of the differentially expressed proteins, one starts experiencing a disturbing déjà vu. The same proteins seem to predominate regardless of the experiment, tissue...