Daniel Varon Silva
Overview
Explore the profile of Daniel Varon Silva including associated specialties, affiliations and a list of published articles.
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38
Citations
526
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Recent Articles
1.
Banerjee P, Silva D, Lipowsky R, Santer M
Glycobiology
. 2022 Oct;
32(11):933-948.
PMID: 36197124
Many proteins are anchored to the cell surface of eukaryotes using a unique family of glycolipids called glycosylphosphatidylinositol (GPI) anchors. These glycolipids also exist without a covalently bound protein, in...
2.
Tyrikos-Ergas T, Gim S, Huang J, Pinzon Martin S, Silva D, Seeberger P, et al.
Nat Commun
. 2022 Jul;
13(1):3954.
PMID: 35804023
Bacterial biofilm matrices are nanocomposites of proteins and polysaccharides with remarkable mechanical properties. Efforts understanding and tuning the protein component have been extensive, whereas the polysaccharide part remained mostly overlooked....
3.
Wang Y, Menon A, Maki Y, Liu Y, Iwasaki Y, Fujita M, et al.
Proc Natl Acad Sci U S A
. 2022 Mar;
119(14):e2115083119.
PMID: 35344438
SignificanceScramblases translocate lipids across the lipid bilayer without consumption of ATP, thereby regulating lipid distributions in cellular membranes. Cytosol-to-lumen translocation across the endoplasmic reticulum (ER) membrane is a common process...
4.
Guerrero P, Murakami Y, Malik A, Seeberger P, Kinoshita T, Silva D
ACS Chem Biol
. 2021 Oct;
16(11):2297-2306.
PMID: 34618440
The attachment of proteins to the cell membrane using a glycosylphosphatidylinositol (GPI) anchor is a ubiquitous process in eukaryotic cells. Deficiencies in the biosynthesis of GPIs and the concomitant production...
5.
Malik A, Seeberger P, Brezesinski G, Silva D
Chemphyschem
. 2021 Feb;
22(8):757-763.
PMID: 33586851
Glycosylphosphatidylinositols (GPIs) are complex glycolipids found in free form or anchoring proteins to the outer leaflet of the cell membrane in eukaryotes. GPIs have been associated with the formation of...
6.
Malik A, Seeberger P, Silva D
Adv Biochem Eng Biotechnol
. 2020 Nov;
175:201-230.
PMID: 33188456
Carbohydrates are functional and structural biomolecules with structures ranging from monosaccharides to polysaccharides. They are naturally found as pure glycans or attached to lipids and proteins forming glycoconjugates. The biosynthesis...
7.
Vogt M, Schmitz G, Silva D, Mosch H, Essen L
Proc Natl Acad Sci U S A
. 2020 Aug;
117(36):22061-22067.
PMID: 32839341
The correct distribution and trafficking of proteins are essential for all organisms. Eukaryotes evolved a sophisticated trafficking system which allows proteins to reach their destination within highly compartmentalized cells. One...
8.
Shanina E, Siebs E, Zhang H, Silva D, Joachim I, Titz A, et al.
Glycobiology
. 2020 Jun;
31(2):159-165.
PMID: 32573695
The carbohydrate-binding protein LecA (PA-IL) from Pseudomonas aeruginosa plays an important role in the formation of biofilms in chronic infections. Development of inhibitors to disrupt LecA-mediated biofilms is desired but...
9.
Echeverri D, Garg M, Silva D, Orozco J
Talanta
. 2020 Jun;
217:121117.
PMID: 32498834
Glycosylphosphatidylinositol anchored proteins (GPI-APs) are natural conjugates in the plasma membrane of eukaryotic cells that result from the attachment of a glycolipid to the C-terminus of many proteins. GPI-APs play...
10.
A Glycan Array-Based Assay for the Identification and Characterization of Plant Glycosyltransferases
Ruprecht C, Bartetzko M, Senf D, Lakhina A, Smith P, Soto M, et al.
Angew Chem Int Ed Engl
. 2020 May;
59(30):12493-12498.
PMID: 32396713
Growing plants with modified cell wall compositions is a promising strategy to improve resistance to pathogens, increase biomass digestibility, and tune other important properties. In order to alter biomass architecture,...