Daniel V Brown
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Explore the profile of Daniel V Brown including associated specialties, affiliations and a list of published articles.
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13
Citations
256
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Recent Articles
1.
Brown D, Swierczak A, You Y, You Y, Amann-Zalcenstein D, Hickey P, et al.
Data Brief
. 2024 Dec;
57:111096.
PMID: 39633974
Single-cell RNA sequencing (scRNA-seq) is a powerful technology that enables the measurement of gene expression in individual cells. Such precision provides insights into cellular heterogeneity that bulk methods might overlook....
2.
Brown D, Anttila C, Ling L, Grave P, Baldwin T, Munnings R, et al.
Genomics
. 2024 Jan;
116(2):110793.
PMID: 38220132
Single-cell RNA sequencing (scRNA-Seq) has emerged as a powerful tool for understanding cellular heterogeneity and function. However the choice of sample multiplexing reagents can impact data quality and experimental outcomes....
3.
Amarasinghe S, Yang P, Voogd O, Yang H, Du M, Su S, et al.
NAR Genom Bioinform
. 2023 Dec;
5(4):lqad105.
PMID: 38046273
scPipe is a flexible R/Bioconductor package originally developed to analyse platform-independent single-cell RNA-Seq data. To expand its preprocessing capability to accommodate new single-cell technologies, we further developed scPipe to handle...
4.
Borger J, Ng A, Anderton H, Ashdown G, Auld M, Blewitt M, et al.
Immunol Cell Biol
. 2023 Sep;
101(10):923-935.
PMID: 37721869
The emergence of large language models (LLMs) and assisted artificial intelligence (AI) technologies have revolutionized the way in which we interact with technology. A recent symposium at the Walter and...
5.
Zhang S, Coughlan H, Ashayeripanah M, Seizova S, Kueh A, Brown D, et al.
Sci Immunol
. 2021 Apr;
6(58).
PMID: 33811060
The functional diversification of dendritic cells (DCs) is a key step in establishing protective immune responses. Despite the importance of DC lineage diversity, its genetic basis is not fully understood....
6.
Travnickova J, Wojciechowska S, Khamseh A, Gautier P, Brown D, Lefevre T, et al.
Cancer Res
. 2019 Oct;
79(22):5769-5784.
PMID: 31582381
The melanocyte-inducing transcription factor (MITF)-low melanoma transcriptional signature is predictive of poor outcomes for patients, but little is known about its biological significance, and animal models are lacking. Here, we...
7.
Brown D, Stylli S, Kaye A, Mantamadiotis T
Adv Exp Med Biol
. 2019 May;
1139:1-21.
PMID: 31134492
Glioblastoma is a primary tumor of the brain with a poor prognosis. Pathological examination shows that this disease is characterized by intra-tumor morphological heterogeneity, while numerous and ongoing genomic analysis...
8.
Atkins R, Stylli S, Kurganovs N, Mangiola S, Nowell C, Ware T, et al.
Exp Cell Res
. 2018 Dec;
374(2):353-364.
PMID: 30562483
Glioblastoma (GBM) tumor cells exhibit drug resistance and are highly infiltrative. GBM stem cells (GSCs), which have low proliferative capacity are thought to be one of the sources of resistant...
9.
Daniel P, Filiz G, Brown D, Christie M, Waring P, Zhang Y, et al.
Neuro Oncol
. 2018 May;
20(10):1344-1355.
PMID: 29718345
Background: Hyperactivation of phosphoinositide 3-kinase (PI3K) signaling is common in cancers, but the precise role of the pathway in glioma biology remains to be determined. Some understanding of PI3K signaling...
10.
Brown D, Filiz G, Daniel P, Hollande F, Dworkin S, Amiridis S, et al.
PLoS One
. 2017 Feb;
12(2):e0172791.
PMID: 28241049
Glioblastoma (GBM) is a heterogeneous tumor of the brain with a poor prognosis due to recurrence and drug resistance following therapy. Genome-wide profiling has revealed the existence of distinct GBM...