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Daniel T Montoro

Explore the profile of Daniel T Montoro including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 2629
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Recent Articles
1.
Yuan F, Gasser G, Lemire E, Montoro D, Jagadeesh K, Zhang Y, et al.
Nature . 2023 Sep; 621(7980):857-867. PMID: 37730992
Speciation leads to adaptive changes in organ cellular physiology and creates challenges for studying rare cell-type functions that diverge between humans and mice. Rare cystic fibrosis transmembrane conductance regulator (CFTR)-rich...
2.
Kwok S, Montoro D, Haber A, Yun S, Vinarsky V
Elife . 2023 Apr; 12. PMID: 37083555
Despite advances in high-dimensional cellular analysis, the molecular profiling of dynamic behaviors of cells in their native environment remains a major challenge. We present a method that allows us to...
3.
Jagadeesh K, Dey K, Montoro D, Mohan R, Gazal S, Engreitz J, et al.
Nat Genet . 2022 Sep; 54(10):1479-1492. PMID: 36175791
Genome-wide association studies provide a powerful means of identifying loci and genes contributing to disease, but in many cases, the related cell types/states through which genes confer disease risk remain...
4.
Jagadeesh K, Dey K, Montoro D, Mohan R, Gazal S, Engreitz J, et al.
bioRxiv . 2021 Nov; PMID: 34845454
Genome-wide association studies (GWAS) provide a powerful means to identify loci and genes contributing to disease, but in many cases the related cell types/states through which genes confer disease risk...
5.
Melms J, Biermann J, Huang H, Wang Y, Nair A, Tagore S, et al.
Nature . 2021 Oct; 598(7882):E2. PMID: 34625743
No abstract available.
6.
Delorey T, Ziegler C, Heimberg G, Normand R, Yang Y, Segerstolpe A, et al.
Nature . 2021 Apr; 595(7865):107-113. PMID: 33915569
COVID-19, which is caused by SARS-CoV-2, can result in acute respiratory distress syndrome and multiple organ failure, but little is known about its pathophysiology. Here we generated single-cell atlases of...
7.
Melms J, Biermann J, Huang H, Wang Y, Nair A, Tagore S, et al.
Nature . 2021 Apr; 595(7865):114-119. PMID: 33915568
Respiratory failure is the leading cause of death in patients with severe SARS-CoV-2 infection, but the host response at the lung tissue level is poorly understood. Here we performed single-nucleus...
8.
Mou H, Yang Y, Riehs M, Barrios J, Shivaraju M, Haber A, et al.
Cell Rep . 2021 Apr; 35(3):109011. PMID: 33882306
Pulmonary neuroendocrine cells (PNECs) have crucial roles in airway physiology and immunity by producing bioactive amines and neuropeptides (NPs). A variety of human diseases exhibit PNEC hyperplasia. Given accumulated evidence...
9.
Delorey T, Ziegler C, Heimberg G, Normand R, Yang Y, Segerstolpe A, et al.
bioRxiv . 2021 Mar; PMID: 33655247
The SARS-CoV-2 pandemic has caused over 1 million deaths globally, mostly due to acute lung injury and acute respiratory distress syndrome, or direct complications resulting in multiple-organ failures. Little is...
10.
Muus C, Luecken M, Eraslan G, Sikkema L, Waghray A, Heimberg G, et al.
Nat Med . 2021 Mar; 27(3):546-559. PMID: 33654293
Angiotensin-converting enzyme 2 (ACE2) and accessory proteases (TMPRSS2 and CTSL) are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) cellular entry, and their expression may shed light on viral...