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Daniel Sinnett

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Articles 225
Citations 3401
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Recent Articles
1.
Benmoussa A, Kientega T, Morel S, B Cardin G, Berard S, Wajnberg M, et al.
Nutr Cancer . 2025 Mar; :1-16. PMID: 40059323
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. Contributory factors such as inflammation and oxidative stress, in response to drug therapies, may induce premature aging and cellular senescence...
2.
Elder E, Lemieux A, Legault L, Caron M, Bertrand-Lehouillier V, Dupas T, et al.
Nucleic Acids Res . 2025 Feb; 53(4). PMID: 39997223
Epigenetic mechanisms are crucial for developmental programming and can be disrupted by environmental stressors, increasing susceptibility to disease. This has sparked interest in therapies for restoring epigenetic balance, but it...
3.
Clime L, Pavel C, Malic L, Nassif C, Geissler M, Lupu N, et al.
Materials (Basel) . 2025 Jan; 18(2). PMID: 39859686
A novel approach to protein quantification utilizing a microfluidic platform activated by a magnetic assembly of functionalized magnetic beads around soft magnetic capture centers is presented. Functionalized magnetic beads, known...
4.
Delorme J, Dima A, Belanger V, Napartuk M, Bouchard I, Meloche C, et al.
Cancers (Basel) . 2025 Jan; 17(1. PMID: 39796783
Background/objectives: Pediatric cancer survivors are at greater risk of cardiometabolic complications than their peers. This study evaluates the preliminary impact of the VIE (Valorization, Implication, Education) intervention, which integrates nutrition,...
5.
Pelland-Marcotte M, Belaktib A, Droit A, Remy M, Clement J, Bianco S, et al.
J Thromb Haemost . 2024 Dec; 23(3):1009-1022. PMID: 39694444
Background: Venous thromboembolism (VTE) is a frequent complication of childhood acute lymphoblastic leukemia (ALL). Objectives: We aimed to identify molecular markers and signatures of the leukemia microenvironment associated with VTE...
6.
Ghantous A, Nussle S, Nassar F, Spitz N, Novoloaca A, Krali O, et al.
Mol Cancer . 2024 Oct; 23(1):238. PMID: 39443995
Background: Cancer is the leading cause of disease-related mortality in children. Causes of leukemia, the most common form, are largely unknown. Growing evidence points to an origin in-utero, when global...
7.
Harvey A, Caru M, Corcia C, Bertrand E, Gagne V, Dandekar S, et al.
Int J Cancer . 2024 Sep; 156(2):403-416. PMID: 39244732
An example of chemotherapy-induced cardiotoxicity in cancer survivors is acquired long QT syndrome (aLQTS), which may cause serious yet preventable life-threatening consequences. Our objective was to identify and characterize childhood...
8.
Couture C, Caron M, St-Onge P, Brien M, Sinnett D, Dal Soglio D, et al.
Placenta . 2024 Jul; 154:184-192. PMID: 39042974
Introduction: Pregnancy complications, including preeclampsia (PE), preterm birth (PTB), and intra-uterine growth restriction (IUGR) have individually been associated with inflammation but the combined comparative analysis of their placental profiles at...
9.
Kientega T, Marcoux S, Bourbonnais J, Montpetit J, Caru M, B Cardin G, et al.
Blood Cancer J . 2024 Jun; 14(1):96. PMID: 38871704
Childhood acute lymphoblastic leukemia (cALL) survivors suffer early-onset chronic diseases classically associated with aging. Normal aging is accompanied by organ dysfunctions, including immunological ones. We hypothesize that thymic immunosenescence occurs...
10.
Brochu A, Kairy D, Alos N, Laverdiere C, Sinnett D, Sultan S, et al.
J Cancer Surviv . 2024 May; PMID: 38787491
Purpose: Long-term musculoskeletal complications represent a growing burden for survivors of childhood acute lymphoblastic leukemia (cALL). This study aimed to describe physical impairments, activity limitations, and participation restrictions in a...