Daniel Segre
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Explore the profile of Daniel Segre including associated specialties, affiliations and a list of published articles.
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96
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3940
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Recent Articles
1.
Peng H, Kotelnikov S, Egbert M, Ofaim S, Stevens G, Phanse S, et al.
Cell
. 2025 Jan;
188(5):1441-1455.e15.
PMID: 39862855
Knowledge of protein-metabolite interactions can enhance mechanistic understanding and chemical probing of biochemical processes, but the discovery of endogenous ligands remains challenging. Here, we combined rapid affinity purification with precision...
2.
Lu A, Dukovski I, Segre D
bioRxiv
. 2024 Nov;
PMID: 39605584
Viral pathogens, like SARS-CoV-2, hijack the host's macromolecular production machinery, imposing an energetic burden that is distributed across cellular metabolism. To explore the dynamic metabolic tension between the host's survival...
3.
Dukovski I, Golden L, Zhang J, Osborne M, Segre D, Korolev K
bioRxiv
. 2024 Nov;
PMID: 39502364
Microbial colony growth is shaped by the physics of biomass propagation and nutrient diffusion, and by the metabolic reactions that organisms activate as a function of the surrounding environment. While...
4.
Scott H, Segre D
Ann Rev Mar Sci
. 2024 Sep;
17(1):593-620.
PMID: 39259978
Ocean metabolism constitutes a complex, multiscale ensemble of biochemical reaction networks harbored within and between the boundaries of a myriad of organisms. Gaining a quantitative understanding of how these networks...
5.
Sher D, Segre D, Follows M
Nat Microbiol
. 2024 Aug;
9(8):1940-1953.
PMID: 39107418
Metabolism is the complex network of chemical reactions occurring within every cell and organism, maintaining life, mediating ecosystem processes and affecting Earth's climate. Experiments and models of microbial metabolism often...
6.
Lapidot R, Faits T, Ismail A, Allam M, Khumalo Z, MacLeod W, et al.
Gates Open Res
. 2024 Jul;
6:48.
PMID: 39050991
Background: Infants suffering from lower respiratory tract infections (LRTIs) have distinct nasopharyngeal (NP) microbiome profiles that correlate with severity of disease. Whether these profiles precede the infection or are a...
7.
Moyer D, Reimertz J, Segre D, Fuxman Bass J
bioRxiv
. 2024 Jul;
PMID: 38979177
Background: Genome-Scale Metabolic Models (GSMMs) are used for numerous tasks requiring computational estimates of metabolic fluxes, from predicting novel drug targets to engineering microbes to produce valuable compounds. A key...
8.
Silverstein M, Bhatnagar J, Segre D
Nat Ecol Evol
. 2024 Jul;
8(8):1493-1504.
PMID: 38956426
Microbial communities are shaped by environmental metabolites, but the principles that govern whether different communities will converge or diverge in any given condition remain unknown, posing fundamental questions about the...
9.
Givati S, Forchielli E, Aharonovich D, Barak N, Weissberg O, Belkin N, et al.
Appl Environ Microbiol
. 2024 Jun;
90(7):e0025624.
PMID: 38920365
Importance: A major goal of microbial ecology is to predict the dynamics of natural communities based on the identity of the organisms, their physiological traits, and their genomes. Our results...
10.
Herbst K, Wang T, Forchielli E, Thommes M, Paschalidis I, Segre D
Commun Biol
. 2024 Apr;
7(1):407.
PMID: 38570615
The interpretation of complex biological datasets requires the identification of representative variables that describe the data without critical information loss. This is particularly important in the analysis of large phenotypic...