Daniel Schnepf
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Explore the profile of Daniel Schnepf including associated specialties, affiliations and a list of published articles.
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25
Citations
1006
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Recent Articles
1.
Wang X, Dong M, Wu X, Schnepf D, Thiel J, Sun W, et al.
J Virol
. 2025 Feb;
:e0141324.
PMID: 39902863
Type III interferons (IFNs) primarily act on epithelial cells and protect against virus infection of the mucosa, whereas type I IFNs act more systemically. To date, it has been unknown...
2.
Ko C, Cheng C, Mistretta D, Ambike S, Sacherl J, Velkov S, et al.
J Med Virol
. 2025 Jan;
97(1):e70156.
PMID: 39760326
SARS-CoV-2 infection is accompanied by elevated liver enzymes, and patients with pre-existing liver conditions experience more severe disease. While it was known that SARS-CoV-2 infects human hepatocytes, our study determines...
3.
Fricke C, Ulrich L, Kochmann J, Gergen J, Kovacikova K, Roth N, et al.
Mol Ther Nucleic Acids
. 2024 Nov;
35(4):102360.
PMID: 39524696
Coronavirus disease 2019 (COVID-19) mRNA vaccines that have contributed to controlling the SARS-CoV-2 pandemic induce specific serum antibodies, which correlate with protection. However, the neutralizing capacity of antibodies for emerging...
4.
Calvanese A, Cecconi V, Staheli S, Schnepf D, Nater M, Pereira P, et al.
Eur J Immunol
. 2024 Jul;
54(10):e2451207.
PMID: 38980268
Tertiary lymphoid structures (TLS) resemble follicles of secondary lymphoid organs and develop in nonlymphoid tissues during inflammation and cancer. Which cell types and signals drive the development of TLS is...
5.
Gautam A, Boyd D, Nikhar S, Zhang T, Siokas I, Van de Velde L, et al.
Nature
. 2024 Apr;
628(8009):835-843.
PMID: 38600381
Severe influenza A virus (IAV) infections can result in hyper-inflammation, lung injury and acute respiratory distress syndrome (ARDS), for which there are no effective pharmacological therapies. Necroptosis is an attractive...
6.
Bergant V, Schnepf D, de Andrade Kratzig N, Hubel P, Urban C, Engleitner T, et al.
Nat Commun
. 2023 Aug;
14(1):4906.
PMID: 37582777
Changes of mRNA 3'UTRs by alternative polyadenylation (APA) have been associated to numerous pathologies, but the mechanisms and consequences often remain enigmatic. By combining transcriptomics, proteomics and recombinant viruses we...
7.
Mossad O, Nent E, Woltemate S, Folschweiller S, Buescher J, Schnepf D, et al.
Nat Aging
. 2023 Apr;
1(12):1127-1136.
PMID: 37117525
Understanding the physiological origins of age-related cognitive decline is of critical importance given the rising age of the world's population. Previous work in animal models has established a strong link...
8.
Jaki L, Weigang S, Kern L, Kramme S, Wrobel A, Grawitz A, et al.
Nat Commun
. 2023 Apr;
14(1):1999.
PMID: 37037847
Monoclonal antibodies (mAbs) directed against the spike of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are effective therapeutic options to combat infections in high-risk patients. Here, we report the adaptation...
9.
Murillo-Leon M, Bastidas-Quintero A, Endres N, Schnepf D, Delgado-Betancourt E, Ohnemus A, et al.
bioRxiv
. 2023 Mar;
PMID: 36865100
Interferons are essential for innate and adaptive immune responses against a wide variety of pathogens. Interferon lambda (IFN-λ) protects mucosal barriers during pathogen exposure. The intestinal epithelium is the first...
10.
Beer J, Crotta S, Breithaupt A, Ohnemus A, Becker J, Sachs B, et al.
J Exp Med
. 2022 Sep;
219(12).
PMID: 36129445
Severity of COVID-19 shows an extraordinary correlation with increasing age. We generated a mouse model for severe COVID-19 and show that the age-dependent disease severity is caused by the disruption...