Daniel Ramandi
Overview
Explore the profile of Daniel Ramandi including associated specialties, affiliations and a list of published articles.
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7
Citations
24
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Recent Articles
1.
Ramandi D, Sepers M, Wang Z, Han B, Woodard C, Murphy T, et al.
PLoS One
. 2025 Feb;
20(2):e0318663.
PMID: 39946413
Huntington disease (HD) is a genetic neurodegenerative disorder characterized by progressive motor dysfunction, cognitive decline, and neuropsychiatric symptoms. Assessing early motor skill deficits in HD mouse models is challenging with...
2.
Cheng J, Koch E, Ramandi D, Mackay J, OLeary T, Rees-Jones W, et al.
Neurobiol Dis
. 2024 Dec;
205():106774.
PMID: 39716682
Background: Altered balance between striatal direct and indirect pathways contributes to early motor, cognitive and psychiatric symptoms in Huntington disease (HD). While degeneration of striatal D2-type dopamine receptor (D2)-expressing indirect...
3.
Koch E, Cheng J, Ramandi D, Sepers M, Hsu A, Fong T, et al.
BMC Biol
. 2024 May;
22(1):121.
PMID: 38783261
Background: Huntington disease (HD) is a neurodegenerative disorder with complex motor and behavioural manifestations. The Q175 knock-in mouse model of HD has gained recent popularity as a genetically accurate model...
4.
Nassrallah W, Ramandi D, Cheng J, Oh J, Mackay J, Sepers M, et al.
Neurobiol Dis
. 2023 Nov;
189:106360.
PMID: 37992785
Cortical-striatal synaptic dysfunction, including enhanced toxic signaling by extrasynaptic N-methyl-d-aspartate receptors (eNMDARs), precedes neurodegeneration in Huntington disease (HD). A previous study showed Activin A, whose transcription is upregulated by calcium...
5.
Wang Y, Ramandi D, Sepers M, Mackay J, Raymond L
Hum Mol Genet
. 2023 Nov;
33(5):387-399.
PMID: 37947186
The neurodegenerative disorder, Huntington disease (HD), manifests as disorders of movement, cognition and mood. Although studies report abnormal corticostriatal synaptic function early in HD mouse models, less is known about...
6.
Ramandi D, Michelson N, Raymond L, Murphy T
Neurophotonics
. 2023 Jan;
10(1):015001.
PMID: 36694618
Significance: Genetically encoded optical probes to image calcium levels in neurons are used widely as a real-time measure of neuronal activity in the brain. Mesoscale calcium imaging through a cranial...
7.
Sepers M, Mackay J, Koch E, Xiao D, Mohajerani M, Chan A, et al.
Neurobiol Dis
. 2022 Apr;
169:105740.
PMID: 35460870
Huntington disease (HD), a hereditary neurodegenerative disorder, manifests as progressively impaired movement and cognition. Although early abnormalities of neuronal activity in striatum are well established in HD models, there are...
8.
Ramandi D, Elahdadi Salmani M, Moghimi A, Lashkarbolouki T, Fereidoni M
PLoS One
. 2021 Jan;
16(1):e0246068.
PMID: 33507976
It is known that hippocampal epileptogenesis is accompanied by hyperexcitability, glutamate-related neuronal dysfunctions and consequently cognitive deficits. However, the neuroprotective role of astrocytic glutamate uptake through the Glutamate Transporter-1 (GLT-1)...