Daniel Martin-Perez
Overview
Explore the profile of Daniel Martin-Perez including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
848
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0
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Recent Articles
1.
Garcia-Quintans N, Sacristan S, Marquez-Lopez C, Sanchez-Ramos C, Martinez-de-Benito F, Siniscalco D, et al.
Nat Commun
. 2023 Oct;
14(1):6461.
PMID: 37833253
The most prevalent genetic form of inherited arrhythmogenic cardiomyopathy (ACM) is caused by mutations in desmosomal plakophilin-2 (PKP2). By studying pathogenic deletion mutations in the desmosomal protein PKP2, here we...
2.
Gonzalez-Guerra A, Roche-Molina M, Garcia-Quintans N, Sanchez-Ramos C, Martin-Perez D, Lytvyn M, et al.
Int J Mol Sci
. 2021 Aug;
22(16).
PMID: 34445154
The continuous relationship between blood pressure (BP) and cardiovascular events makes the distinction between elevated BP and hypertension based on arbitrary cut-off values for BP. Even mild BP elevations manifesting...
3.
Forte D, Garcia-Fernandez M, Sanchez-Aguilera A, Stavropoulou V, Fielding C, Martin-Perez D, et al.
Cell Metab
. 2020 Sep;
32(5):829-843.e9.
PMID: 32966766
Like normal hematopoietic stem cells, leukemic stem cells depend on their bone marrow (BM) microenvironment for survival, but the underlying mechanisms remain largely unknown. We have studied the contribution of...
4.
Garcia-Garcia A, Korn C, Garcia-Fernandez M, Domingues O, Villadiego J, Martin-Perez D, et al.
Blood
. 2018 Oct;
133(3):224-236.
PMID: 30361261
Hematopoietic stem and progenitor cells (HSPCs) and leukocytes circulate between the bone marrow (BM) and peripheral blood following circadian oscillations. Autonomic sympathetic noradrenergic signals have been shown to regulate HSPC...
5.
Sanchez-Aguilera A, Arranz L, Martin-Perez D, Garcia-Garcia A, Stavropoulou V, Kubovcakova L, et al.
Cell Stem Cell
. 2014 Dec;
15(6):791-804.
PMID: 25479752
Estrogens are potent regulators of mature hematopoietic cells; however, their effects on primitive and malignant hematopoietic cells remain unclear. Using genetic and pharmacological approaches, we observed differential expression and function...
6.
Isern J, Garcia-Garcia A, Martin A, Arranz L, Martin-Perez D, Torroja C, et al.
Elife
. 2014 Sep;
3:e03696.
PMID: 25255216
Mesenchymal stem cells (MSCs) and osteolineage cells contribute to the hematopoietic stem cell (HSC) niche in the bone marrow of long bones. However, their developmental relationships remain unclear. In this...
7.
Arranz L, Sanchez-Aguilera A, Martin-Perez D, Isern J, Langa X, Tzankov A, et al.
Nature
. 2014 Jul;
512(7512):78-81.
PMID: 25043017
Myeloproliferative neoplasms (MPNs) are diseases caused by mutations in the haematopoietic stem cell (HSC) compartment. Most MPN patients have a common acquired mutation of Janus kinase 2 (JAK2) gene in...
8.
Isern J, Martin-Antonio B, Ghazanfari R, Martin A, Lopez J, Del Toro R, et al.
Cell Rep
. 2013 Apr;
3(5):1714-24.
PMID: 23623496
Strategies for expanding hematopoietic stem cells (HSCs) include coculture with cells that recapitulate their natural microenvironment, such as bone marrow stromal stem/progenitor cells (BMSCs). Plastic-adherent BMSCs may be insufficient to...
9.
Martin-Perez D, Piris M, Sanchez-Beato M
Blood
. 2010 Aug;
116(25):5465-75.
PMID: 20716771
The Polycomb group (PcG) of proteins is a major mechanism of epigenetic regulation that has been broadly linked to cancer. This system can repress gene expression by chromatin modification and...
10.
Martin-Perez D, Sanchez E, Maestre L, Suela J, Vargiu P, Di Lisio L, et al.
Am J Pathol
. 2010 Jun;
177(2):930-42.
PMID: 20558579
Polycomb proteins are known to be of great importance in human cancer pathogenesis. SUZ12 is a component of the Polycomb PRC2 complex that, along with EZH2, is involved in embryonic...