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Daniel M Rotroff

Explore the profile of Daniel M Rotroff including associated specialties, affiliations and a list of published articles. Areas
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Articles 72
Citations 2111
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Recent Articles
1.
Lv L, Wang Y, Xie L, Noone J, Alvarez S, Zhang Y, et al.
Value Health . 2025 Feb; PMID: 39947393
Objectives: The population-level impact of newer glucagon-like peptide-1 receptor agonist (GLP-1 RA) treatments on patients with type 2 diabetes remains unclear. Therefore, this study investigated the association of newer GLP-1...
2.
Mariam A, Javidi H, Zabor E, Zhao R, Radivoyevitch T, Rotroff D
PLOS Digit Health . 2024 Oct; 3(10):e0000628. PMID: 39405315
Longitudinal electronic health records (EHR) can be utilized to identify patterns of disease development and progression in real-world settings. Unsupervised temporal matching algorithms are being repurposed to EHR from signal...
3.
Daniels N, Hershberger C, Kerosky M, Wehrle C, Raj R, Aykun N, et al.
Int J Mol Sci . 2024 Sep; 25(18). PMID: 39337628
Chronic liver diseases, including non-alcoholic fatty liver disease (NAFLD), cirrhosis, and hepatocellular carcinoma (HCC), continue to be a global health burden with a rise in incidence and mortality, necessitating a...
4.
Banerjee R, Wehrle C, Wang Z, Wilcox J, Uppin V, Varadharajan V, et al.
Biomedicines . 2024 Sep; 12(9). PMID: 39335460
Methods: Forty-one patients with HCC and 96 healthy controls were enrolled from surgical clinics at the Cleveland Clinic from 2016 to 2020. Gut microbiota-derived circulating metabolites detectable in plasma were...
5.
Sharma A, Mariam A, Zacherle E, Milinovich A, Bauman J, Sugano D, et al.
Diabetes Obes Metab . 2024 Aug; 26(11):5347-5357. PMID: 39192531
Aims: To investigate the independent contributions of glycated haemoglobin (HbA1c) reduction and weight loss to clinical outcomes in patients with type 2 diabetes (T2D) treated with antidiabetic drugs, including glucagon-like...
6.
Jayakrishnan T, Sangwan N, Barot S, Farha N, Mariam A, Xiang S, et al.
NPJ Precis Oncol . 2024 Jul; 8(1):146. PMID: 39020083
The incidence of early-onset colorectal cancer (eoCRC) is rising, and its pathogenesis is not completely understood. We hypothesized that machine learning utilizing paired tissue microbiome and plasma metabolome features could...
7.
Breeyear J, Hellwege J, Schroeder P, House J, Poisner H, Mitchell S, et al.
Nat Med . 2024 Jun; 30(9):2480-2488. PMID: 38918629
Diabetes complications occur at higher rates in individuals of African ancestry. Glucose-6-phosphate dehydrogenase deficiency (G6PDdef), common in some African populations, confers malaria resistance, and reduces hemoglobin A1c (HbA1c) levels by...
8.
Hershberger C, Mariam A, Pantalone K, Buse J, Motsinger-Reif A, Rotroff D
Hum Genomics . 2024 Jun; 18(1):70. PMID: 38909264
Introduction: We previously identified a genetic subtype (C4) of type 2 diabetes (T2D), benefitting from intensive glycemia treatment in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial. Here,...
9.
Taiwo M, Huang E, Pathak V, Bellar A, Welch N, Dasarathy J, et al.
JCI Insight . 2024 Apr; 9(9). PMID: 38573776
Diagnostic challenges continue to impede development of effective therapies for successful management of alcohol-associated hepatitis (AH), creating an unmet need to identify noninvasive biomarkers for AH. In murine models, complement...
10.
Javidi H, Mariam A, Alkhaled L, Pantalone K, Rotroff D
J Am Med Inform Assoc . 2024 Mar; 31(6):1227-1238. PMID: 38497983
Objectives: Metabolic disease in children is increasing worldwide and predisposes a wide array of chronic comorbid conditions with severe impacts on quality of life. Tools for early detection are needed...