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Daniel Karl

Explore the profile of Daniel Karl including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 109
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Recent Articles
1.
Lee Y, Koch M, Karl D, Torres-Collado A, Fernando N, Rothrock C, et al.
Cancer Res . 2024 Oct; 84(20):3491. PMID: 39402991
No abstract available.
2.
Mas G, Man N, Nakata Y, Martinez-Caja C, Karl D, Beckedorff F, et al.
J Clin Invest . 2023 May; 133(13). PMID: 37200093
During emergency hematopoiesis, hematopoietic stem cells (HSCs) rapidly proliferate to produce myeloid and lymphoid effector cells, a response that is critical against infection or tissue injury. If unresolved, this process...
3.
Brabson J, Leesang T, Yap Y, Wang J, Lam M, Fang B, et al.
Cell Rep . 2023 Feb; 42(1):112027. PMID: 36848231
TET2 haploinsufficiency is a driving event in myeloid cancers and is associated with a worse prognosis in patients with acute myeloid leukemia (AML). Enhancing residual TET2 activity using vitamin C...
4.
Xu Y, Man N, Karl D, Martinez C, Liu F, Sun J, et al.
Nat Commun . 2019 Oct; 10(1):4925. PMID: 31664040
AML1-ETO (AE) is a fusion transcription factor, generated by the t(8;21) translocation, that functions as a leukemia promoting oncogene. Here, we demonstrate that TATA-Box Binding Protein Associated Factor 1 (TAF1)...
5.
Greenblatt S, Man N, Hamard P, Asai T, Karl D, Martinez C, et al.
Cancer Cell . 2019 Jan; 35(1):156. PMID: 30645972
No abstract available.
6.
Greenblatt S, Man N, Hamard P, Asai T, Karl D, Martinez C, et al.
Cancer Cell . 2018 Nov; 34(5):868. PMID: 30423301
No abstract available.
7.
Greenblatt S, Man N, Hamard P, Asai T, Karl D, Martinez C, et al.
Cancer Cell . 2018 Jun; 33(6):1111-1127.e5. PMID: 29894694
Chromatin-modifying enzymes, and specifically the protein arginine methyltransferases (PRMTs), have emerged as important targets in cancer. Here, we investigated the role of CARM1 in normal and malignant hematopoiesis. Using conditional...
8.
Ray S, Thormann U, Eichelroth M, Budak M, Biehl C, Rupp M, et al.
Biomaterials . 2017 Dec; 157:1-16. PMID: 29216500
The purpose of this work was to investigate new bone formation in macroporous iron foams coated with strontium (FeSr) or bisphosphonate (FeBiP) compared to plain iron foam (Fe) and empty...
9.
Lee Y, Koch M, Karl D, Torres-Collado A, Fernando N, Rothrock C, et al.
Cancer Res . 2010 Jan; 70(3):948-56. PMID: 20103648
Metastasis relies on angiogenesis for tumor expansion. Tumor angiogenesis is restrained by a variety of endogenous inhibitors, including thrombospondin 1 (TSP1). The principal antiangiogenic activity of TSP1 resides in a...