Daniel J Benjamin
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Explore the profile of Daniel J Benjamin including associated specialties, affiliations and a list of published articles.
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53
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Recent Articles
1.
Guan J, Tan T, Nehzati S, Bennett M, Turley P, Benjamin D, et al.
Nat Genet
. 2025 Mar;
PMID: 40065166
Family-based genome-wide association studies (FGWASs) use random, within-family genetic variation to remove confounding from estimates of direct genetic effects (DGEs). Here we introduce a 'unified estimator' that includes individuals without...
2.
Kweon H, Burik C, Ning Y, Ahlskog R, Xia C, Abner E, et al.
Nat Hum Behav
. 2025 Jan;
PMID: 39875632
We conducted a genome-wide association study on income among individuals of European descent (N = 668,288) to investigate the relationship between socio-economic status and health disparities. We identified 162 genomic...
3.
Sidorenko J, Couvy-Duchesne B, Kemper K, Moen G, Bhatta L, Asvold B, et al.
Nat Genet
. 2024 Oct;
56(11):2352-2360.
PMID: 39375568
Linkage studies have successfully mapped loci underlying monogenic disorders, but mostly failed when applied to common diseases. Conversely, genome-wide association studies (GWASs) have identified replicable associations between thousands of SNPs...
4.
Chang A, Huang S, Benjamin D, Schmidt J, Palmer C, Garrison N
J Genet Couns
. 2024 May;
34(1):e1908.
PMID: 38741243
While digital tools, such as the Internet, smartphones, and social media, are an important part of modern society, little is known about the specific role they play in the healthcare...
5.
Bilghese M, Manansala R, Jaishankar D, Jala J, Benjamin D, Kimball M, et al.
bioRxiv
. 2023 Sep;
PMID: 37732240
The effects of assortative mating (AM) on estimates from genetic studies has been receiving increasing attention in recent years. We extend existing AM theory to more general models of sorting...
6.
Wrestling with Social and Behavioral Genomics: Risks, Potential Benefits, and Ethical Responsibility
Meyer M, Appelbaum P, Benjamin D, Callier S, Comfort N, Conley D, et al.
Hastings Cent Rep
. 2023 Apr;
53 Suppl 1:S2-S49.
PMID: 37078667
In this consensus report by a diverse group of academics who conduct and/or are concerned about social and behavioral genomics (SBG) research, the authors recount the often-ugly history of scientific...
7.
Meyer M, Tan T, Benjamin D, Laibson D, Turley P
Science
. 2023 Feb;
379(6632):541-543.
PMID: 36758092
Understanding moral acceptability and willingness to use is crucial for informing policy.
8.
Young A, Nehzati S, Benonisdottir S, Okbay A, Jayashankar H, Lee C, et al.
Nat Genet
. 2022 Jun;
54(6):897-905.
PMID: 35681053
Effects estimated by genome-wide association studies (GWASs) include effects of alleles in an individual on that individual (direct genetic effects), indirect genetic effects (for example, effects of alleles in parents...
9.
Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects
Howe L, Nivard M, Morris T, Hansen A, Rasheed H, Cho Y, et al.
Nat Genet
. 2022 May;
54(5):581-592.
PMID: 35534559
Estimates from genome-wide association studies (GWAS) of unrelated individuals capture effects of inherited variation (direct effects), demography (population stratification, assortative mating) and relatives (indirect genetic effects). Family-based GWAS designs can...
10.
Okbay A, Wu Y, Wang N, Jayashankar H, Bennett M, Nehzati S, et al.
Nat Genet
. 2022 Apr;
54(4):437-449.
PMID: 35361970
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic...