Daniel I Brierley
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Explore the profile of Daniel I Brierley including associated specialties, affiliations and a list of published articles.
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17
Citations
902
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Recent Articles
11.
Holt M, Richards J, Cook D, Brierley D, Williams D, Reimann F, et al.
Diabetes
. 2018 Oct;
68(1):21-33.
PMID: 30279161
Centrally administered glucagon-like peptide 1 (GLP-1) supresses food intake. Here we demonstrate that GLP-1-producing (PPG) neurons in the nucleus tractus solitarii (NTS) are the predominant source of endogenous GLP-1 within...
12.
Card J, Johnson A, Llewellyn-Smith I, Zheng H, Anand R, Brierley D, et al.
J Comp Neurol
. 2018 Jul;
526(14):2149-2164.
PMID: 30019398
Glutamatergic neurons that express pre-proglucagon (PPG) and are immunopositive (+) for glucagon-like peptide-1 (i.e., GLP-1+ neurons) are located within the caudal nucleus of the solitary tract (cNTS) and medullary reticular...
13.
Brierley D, Samuels J, Duncan M, Whalley B, Williams C
Behav Pharmacol
. 2017 Jan;
28(4):280-284.
PMID: 28125508
Nonpsychoactive phytocannabinoids (pCBs) from Cannabis sativa may represent novel therapeutic options for cachexia because of their pleiotropic pharmacological activities, including appetite stimulation. We have recently shown that purified cannabigerol (CBG)...
14.
Brierley D, Samuels J, Duncan M, Whalley B, Williams C
Psychopharmacology (Berl)
. 2016 Aug;
233(19-20):3603-13.
PMID: 27503475
Rationale: The appetite-stimulating properties of cannabis are well documented and have been predominantly attributed to the hyperphagic activity of the psychoactive phytocannabinoid, ∆(9)-tetrahydrocannabinol (∆(9)-THC). However, we have previously shown that...
15.
Brierley D, Samuels J, Duncan M, Whalley B, Williams C
Psychopharmacology (Berl)
. 2015 Oct;
233(2):243-54.
PMID: 26439367
Rationale: Anticipatory nausea (AN) is a poorly controlled side effect experienced by chemotherapy patients. Currently, pharmacotherapy is restricted to benzodiazepine anxiolytics, which have limited efficacy, have significant sedative effects and...
16.
Brierley D, Davidson C
J Psychopharmacol
. 2012 Oct;
27(1):98-108.
PMID: 23076833
Harmine is a β-carboline alkaloid and major component of ayahuasca, a traditional South American psychoactive tea with anecdotal efficacy for treatment of cocaine dependence. Harmine is an inhibitor of monoamine...
17.
Brierley D, Davidson C
Prog Neuropsychopharmacol Biol Psychiatry
. 2012 Jun;
39(2):263-72.
PMID: 22691716
Ayahuasca is a hallucinogenic botanical mixture originating in the Amazon area where it is used ritually, but is now being taken globally. The 2 main constituents of ayahuasca are N,N-dimethyltryptamine...
18.
Brischoux F, Chakraborty S, Brierley D, Ungless M
Proc Natl Acad Sci U S A
. 2009 Mar;
106(12):4894-9.
PMID: 19261850
Midbrain dopamine neurons play central roles in reward processing. It is widely assumed that all dopamine neurons encode the same information. Some evidence, however, suggests functional differences between subgroups of...