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Daniel Hochdorfer

Explore the profile of Daniel Hochdorfer including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 115
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Recent Articles
1.
Xin D, Kurien L, Briggs K, Schimek A, Dambra R, Hochdorfer D, et al.
Mol Ther Methods Clin Dev . 2025 Mar; 33(1):101429. PMID: 40083959
Vesicular stomatitis virus expressing the glycoprotein of the lymphocytic choriomeningitis virus (VSV-GP) is a promising platform for oncolytic viruses and cancer vaccines. In this work, cryoelectron microscopy (cryo-EM) imaging was...
2.
Wawra S, Kessler S, Egel A, Solzin J, Burkert O, Hochdorfer D
Eur Biophys J . 2023 May; 52(4-5):379-386. PMID: 37133524
Determination of the size, density, and mass of viral particles can provide valuable information to support process and formulation studies in clinical development. Analytical ultracentrifugation (AUC), as a first principal...
3.
Hochdorfer D, Businger R, Hotter D, Seifried C, Solzin J
J Virol Methods . 2021 Oct; 299:114318. PMID: 34626683
A robust and precise infectivity assay is a prerequisite for the development and market supply of virus-based biologics. Like other cell-based assays, traditional infectivity assays suffer from high variability and...
4.
Fast L, Mikulicic S, Fritzen A, Schwickert J, Boukhallouk F, Hochdorfer D, et al.
Int J Mol Sci . 2018 Oct; 19(10). PMID: 30279342
Tetraspanins are suggested to regulate the composition of cell membrane components and control intracellular transport, which leaves them vulnerable to utilization by pathogens such as human papillomaviruses (HPV) and cytomegaloviruses...
5.
Stegmann C, Hochdorfer D, Lieber D, Subramanian N, Stohr D, Laib Sampaio K, et al.
PLoS Pathog . 2017 Apr; 13(4):e1006273. PMID: 28403220
Human cytomegalovirus (HCMV) is a widely distributed herpesvirus that causes significant morbidity in immunocompromised hosts. Inhibitors of viral DNA replication are available, but adverse effects limit their use. Alternative antiviral...
6.
Hochdorfer D, Florin L, Sinzger C, Lieber D
J Virol . 2016 May; 90(14):6430-42. PMID: 27147745
Unlabelled: Human cytomegalovirus (HCMV), a betaherpesvirus, can cause life-threatening disease in immunocompromised individuals. Viral envelope glycoproteins that mediate binding to and penetration into target cells have been identified previously. In...
7.
Lieber D, Hochdorfer D, Stoehr D, Schubert A, Lotfi R, May T, et al.
Biotechniques . 2015 Sep; 59(3):127-36. PMID: 26345505
Infection of vascular endothelial cells (ECs) is assumed to contribute to dissemination of human cytomegalovirus (HCMV). Investigation of virus-host interactions in ECs such as human umbilical vein endothelial cells (HUVECs)...