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Daniel Gonzalez-Bohorquez

Explore the profile of Daniel Gonzalez-Bohorquez including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Bin Imtiaz M, Royall L, Gonzalez-Bohorquez D, Jessberger S
Development . 2022 Jul; 149(20). PMID: 35815653
Asymmetric segregation of cellular components regulates the fate and behavior of somatic stem cells. Similar to dividing budding yeast and precursor cells in Caenorhabditis elegans, it has been shown that...
2.
Denoth-Lippuner A, Royall L, Gonzalez-Bohorquez D, Machado D, Jessberger S
STAR Protoc . 2022 Feb; 3(1):101129. PMID: 35118433
Pluripotent stem cell-derived human cortical organoids allow for the analysis of stem cell behavior and neurogenesis in neural tissues. Delivery of plasmid DNA into organoids permits visualization of individual cells,...
3.
Cole J, Del Castillo J, Gut G, Gonzalez-Bohorquez D, Pelkmans L, Jessberger S
Elife . 2022 Jan; 11. PMID: 35089129
Advancing age causes reduced hippocampal neurogenesis, associated with age-related cognitive decline. The spatial relationship of age-induced alterations in neural stem cells (NSCs) and surrounding cells within the hippocampal niche remains...
4.
Gonzalez-Bohorquez D, Gallego Lopez I, Jaeger B, Pfammatter S, Bowers M, Semenkovich C, et al.
Proc Natl Acad Sci U S A . 2022 Jan; 119(2). PMID: 34996870
Fate and behavior of neural progenitor cells are tightly regulated during mammalian brain development. Metabolic pathways, such as glycolysis and oxidative phosphorylation, that are required for supplying energy and providing...
5.
Bowers M, Liang T, Gonzalez-Bohorquez D, Zocher S, Jaeger B, Kovacs W, et al.
Cell Stem Cell . 2020 May; 27(1):98-109.e11. PMID: 32386572
Altered neural stem/progenitor cell (NSPC) activity and neurodevelopmental defects are linked to intellectual disability. However, it remains unclear whether altered metabolism, a key regulator of NSPC activity, disrupts human neurogenesis...
6.
Wegleiter T, Buthey K, Gonzalez-Bohorquez D, Hruzova M, Bin Imtiaz M, Abegg A, et al.
Proc Natl Acad Sci U S A . 2019 Nov; 116(51):25688-25696. PMID: 31772009
Neural stem cells (NSCs) generate neurons and glial cells throughout embryonic and postnatal brain development. The role of S-palmitoylation (also referred to as S-acylation), a reversible posttranslational lipid modification of...