Daniel G Sedding
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Explore the profile of Daniel G Sedding including associated specialties, affiliations and a list of published articles.
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51
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1506
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Recent Articles
1.
Dutzmann J, Kefalianakis Z, Kahles F, Daniel J, Gufler H, Wohlgemuth W, et al.
Circ Heart Fail
. 2024 May;
17(5):e010936.
PMID: 38695175
Background: Intermittent fasting has shown positive effects on numerous cardiovascular risk factors. The INTERFAST-MI trial (Intermittent Fasting in Myocardial Infarction) has been designed to study the effects of intermittent fasting...
2.
Dutzmann J, Bode L, Kalies K, Korte L, Knopp K, Kloss F, et al.
Front Cardiovasc Med
. 2022 Aug;
9:956041.
PMID: 36017090
Background: Empagliflozin, an inhibitor of the sodium glucose co-transporter 2 (SGLT2) and developed as an anti-diabetic agent exerts additional beneficial effects on heart failure outcomes. However, the effect of empagliflozin...
3.
Dutzmann J, Knopp K, Kefalianakis Z, Daniel J, Gufler H, Wohlgemuth W, et al.
BMJ Open
. 2022 Apr;
12(4):e050067.
PMID: 35393305
Introduction: Preclinical studies consistently show robust disease-modifying effects of intermittent fasting in animal models of cardiovascular disease. However, the impact of intermittent fasting on cardiovascular endpoints after myocardial infarction has...
4.
Hoyer D, Atti C, Nuding S, Vogt A, Sedding D, Schott A
Am J Case Rep
. 2021 Oct;
22:e932921.
PMID: 34634004
BACKGROUND Allopurinol is the first-line therapy for the treatment of symptomatic hyperuricemia (gout). In clinical practice, there is a tendency to overmedicate asymptomatic patients who have elevated serum urate. Because...
5.
Simnica D, Schultheiss C, Mohme M, Paschold L, Willscher E, Fitzek A, et al.
Clin Transl Immunology
. 2021 Sep;
10(9):e1340.
PMID: 34484739
Objectives: T cells have an essential role in the antiviral defence. Public T-cell receptor (TCR) clonotypes are expanded in a substantial proportion of COVID-19 patients. We set out to exploit...
6.
Paschold L, Simnica D, Willscher E, Vehreschild M, Dutzmann J, Sedding D, et al.
J Clin Invest
. 2020 Oct;
131(1).
PMID: 33064671
A considerable fraction of B cells recognize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with germline-encoded elements of their B cell receptor, resulting in the production of neutralizing and nonneutralizing...
7.
Schultheiss C, Paschold L, Simnica D, Mohme M, Willscher E, von Wenserski L, et al.
Immunity
. 2020 Jul;
53(2):442-455.e4.
PMID: 32668194
We profiled adaptive immunity in COVID-19 patients with active infection or after recovery and created a repository of currently >14 million B and T cell receptor (BCR and TCR) sequences...
8.
Dutzmann J, Haertle M, Daniel J, Kloss F, Musmann R, Kalies K, et al.
Cardiovasc Res
. 2020 May;
117(3):850-862.
PMID: 32353113
Aims: Recent studies revealed that the bromodomain and extra-terminal (BET) epigenetic reader proteins resemble key regulators in the underlying pathophysiology of cancer, diabetes, or cardiovascular disease. However, whether they also...
9.
Tongers J, Sieweke J, Kuhn C, Napp L, Flierl U, Rontgen P, et al.
Circ Heart Fail
. 2020 Mar;
13(3):e005853.
PMID: 32164431
Background: Limited progress has been made in the management of cardiogenic shock (CS). Morbidity and mortality of refractory CS remain high. The effects of mechanical circulatory support (MCS) are promising,...
10.
Stojanovic S, Fiedler J, Bauersachs J, Thum T, Sedding D
Eur Heart J
. 2020 Jan;
41(31):2983-2996.
PMID: 31898722
Inflammation is a hallmark and potent driver of pathological vascular remodelling in atherosclerosis. However, current anti-inflammatory therapeutic strategies have shown mixed results. As an alternative perspective on the conundrum of...