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Daniel Ewerth

Explore the profile of Daniel Ewerth including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Greil C, Felthaus J, Follo M, Ihorst G, Ewerth D, Schuler J, et al.
Am J Cancer Res . 2021 Aug; 11(7):3698-3710. PMID: 34354869
Targeting mitosis by taxanes is one of the most common chemotherapeutic approaches in various malignant solid tumors, but cancer cells may survive antimitotic treatment with attainable concentrations due to mitotic...
2.
Ewerth D, Kreutmair S, Schmidts A, Ihorst G, Follo M, Wider D, et al.
Cell Mol Life Sci . 2018 Oct; 76(2):369-380. PMID: 30357422
Hematopoietic stem and progenitor cells (HSPCs) represent the lifelong source of all blood cells and continuously regenerate the hematopoietic system through differentiation and self-renewal. The process of differentiation is initiated...
3.
Ewerth D, Schmidts A, Hein M, Schnerch D, Kvainickas A, Greil C, et al.
Oncotarget . 2016 Jul; 7(30):48220-48230. PMID: 27374082
The E3 ubiquitin ligase and tumor suppressor APC/CCdh1 is crucial for cell cycle progression, development and differentiation in many cell types. However, little is known about the role of Cdh1...
4.
Schuler J, Ewerth D, Waldschmidt J, Wasch R, Engelhardt M
Expert Opin Biol Ther . 2013 Jun; 13 Suppl 1:S111-23. PMID: 23742200
Introduction: Preclinical models, by definition, are an approximation of reality, and their use in developing anticancer drugs is eagerly explored. Positive clinical correlations have been identified with different test systems,...
5.
Sinnberg T, Menzel M, Ewerth D, Sauer B, Schwarz M, Schaller M, et al.
PLoS One . 2011 Aug; 6(8):e23429. PMID: 21858114
Beta-catenin plays an important role in embryogenesis and carcinogenesis by controlling either cadherin-mediated cell adhesion or transcriptional activation of target gene expression. In many types of cancers nuclear translocation of...
6.
Engelmann D, Knoll S, Ewerth D, Steder M, Stoll A, Putzer B
Cell Mol Life Sci . 2009 Dec; 67(6):931-48. PMID: 20013022
The E2F1 transcription factor enhances apoptosis by DNA damage in tumors lacking p53. To elucidate the mechanism of a potential cooperation between E2F1 and chemotherapy, whole-genome microarrays of chemoresistant tumor...