Daniel DAndrea
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Explore the profile of Daniel DAndrea including associated specialties, affiliations and a list of published articles.
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35
Citations
752
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Recent Articles
1.
Promoter Methylation Leads to Hepatocyte Nuclear Factor 4A Loss and Pancreatic Cancer Aggressiveness
Hatziapostolou M, Koutsioumpa M, Zaitoun A, Polytarchou C, Edderkaoui M, Mahurkar-Joshi S, et al.
Gastro Hep Adv
. 2024 Aug;
3(5):687-702.
PMID: 39165427
Background And Aims: Decoding pancreatic ductal adenocarcinoma heterogeneity and the consequent therapeutic selection remains a challenge. We aimed to characterize epigenetically regulated pathways involved in pancreatic ductal adenocarcinoma progression. Methods:...
2.
Franzese O, Palermo B, Frisullo G, Panetta M, Campo G, DAndrea D, et al.
Oncoimmunology
. 2024 Jun;
13(1):2371051.
PMID: 38915783
Improving cancer immunotherapy efficacy hinges on identifying key T-cell populations critical for tumor control and response to Immune Checkpoint Blockade (ICB). We have recently reported that while the co-expression of...
3.
Garbo S, DAndrea D, Colantoni A, Fiorentino F, Mai A, Ramos A, et al.
Cell Rep
. 2024 Jun;
43(6):114369.
PMID: 38878288
Epitranscriptomics represents a further layer of gene expression regulation. Specifically, N6-methyladenosine (m6A) regulates RNA maturation, stability, degradation, and translation. Regarding microRNAs (miRNAs), while it has been reported that m6A impacts...
4.
Di Modugno F, Di Carlo A, Spada S, Palermo B, DAmbrosio L, DAndrea D, et al.
EBioMedicine
. 2024 Feb;
101:105003.
PMID: 38340557
Background: Tertiary Lymphoid Structures (TLS) correlate with positive outcomes in patients with NSCLC and the efficacy of immune checkpoint blockade (ICB) in cancer. The actin regulatory protein hMENA undergoes tissue-specific...
5.
Palermo B, Franzese O, Frisullo G, DAmbrosio L, Panetta M, Campo G, et al.
J Exp Clin Cancer Res
. 2023 Oct;
42(1):287.
PMID: 37898752
Background: Immune checkpoint blockade (ICB) has significantly prolonged survival of non-small cell lung cancer (NSCLC) patients, although most patients develop mechanisms of resistance. Recently single-cell RNA-sequencing (scRNA-Seq) revealed a huge...
6.
Trono P, Tocci A, Palermo B, Di Carlo A, DAmbrosio L, DAndrea D, et al.
J Immunother Cancer
. 2023 Aug;
11(8).
PMID: 37612043
Background: Understanding how cancer signaling pathways promote an immunosuppressive program which sustains acquired or primary resistance to immune checkpoint blockade (ICB) is a crucial step in improving immunotherapy efficacy. Among...
7.
Turco E, Giovenale A, Sireno L, Mazzoni M, Cammareri A, Marchioretti C, et al.
Cell Death Dis
. 2022 Nov;
13(11):981.
PMID: 36411275
Smith-Magenis syndrome (SMS) is a neurodevelopmental disorder characterized by cognitive and behavioral symptoms, obesity, and sleep disturbance, and no therapy has been developed to alleviate its symptoms or delay disease...
8.
Vecchiotti D, Verzella D, Di Vito Nolfi M, DAndrea D, Flati I, Di Francesco B, et al.
Cells
. 2022 Jul;
11(13).
PMID: 35805202
Prostate cancer (PCa) is the second most frequent cancer in men worldwide. NF-κB seems to play a key role in cell survival, proliferation and invasion, sustaining the heterogeneous multifocal nature...
9.
Sanders B, DAndrea D, Collins M, Rees E, Steward T, Zhu Y, et al.
Nat Commun
. 2022 Jan;
13(1):27.
PMID: 35031607
Coordinated programs of gene expression drive brain development. It is unclear which transcriptional programs, in which cell-types, are affected in neuropsychiatric disorders such as schizophrenia. Here we integrate human genetics...
10.
Watanabe M, Risi R, Tafuri M, Silvestri V, DAndrea D, Raimondo D, et al.
Sci Rep
. 2021 Dec;
11(1):23290.
PMID: 34857816
The Fuegians, ancient inhabitants of Tierra del Fuego, are an exemplary case of a cold-adapted population, since they were capable of living in extreme climatic conditions without any adequate clothing....