Laura Tornatore
Overview
Explore the profile of Laura Tornatore including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
706
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Recent Articles
1.
Tornatore L, Capece D, Sandomenico A, Verzella D, Vecchiotti D, Zazzeroni F, et al.
Methods Mol Biol
. 2021 Jul;
2366:343-356.
PMID: 34236649
Peptides are emerging as an increasingly dependable class of therapeutics in the treatment of cancer and metabolic and cardiovascular diseases, which are all areas of high interest to the pharmaceutical...
2.
Capece D, DAndrea D, Begalli F, Goracci L, Tornatore L, Alexander J, et al.
J Clin Invest
. 2021 Apr;
131(11).
PMID: 33878036
The ability to adapt to low-nutrient microenvironments is essential for tumor cell survival and progression in solid cancers, such as colorectal carcinoma (CRC). Signaling by the NF-κB transcription factor pathway...
3.
Sandomenico A, Di Rienzo L, Calvanese L, Iaccarino E, DAuria G, Falcigno L, et al.
Biomedicines
. 2021 Jan;
9(1).
PMID: 33396582
GADD45β/MKK7 complex is a non-redundant, cancer cell-restricted survival module downstream of the NF-kB survival pathway, and it has a pathogenically critical role in multiple myeloma, an incurable malignancy of plasma...
4.
Tornatore L, De Luca M, Ciccarello M, Benedetti M
Int J Rehabil Res
. 2020 May;
43(3):240-246.
PMID: 32459670
Total knee replacement (TKR) is continuously increasing with significantly faster recovery times. Soft tissue pain and edema of operated limbs play an important role in early functional recovery. The present...
5.
Tornatore L, Capece D, DAndrea D, Begalli F, Verzella D, Bennett J, et al.
Toxicol Rep
. 2019 May;
6:369-379.
PMID: 31080744
Aberrant NF-κB activity drives oncogenesis and cell survival in multiple myeloma (MM) and many other cancers. However, despite an aggressive effort by the pharmaceutical industry over the past 30 years,...
6.
Tornatore L, Capece D, DAndrea D, Begalli F, Verzella D, Bennett J, et al.
Br J Haematol
. 2018 Sep;
185(3):588-592.
PMID: 30255568
No abstract available.
7.
Rega C, Russo R, Foca A, Sandomenico A, Iaccarino E, Raimondo D, et al.
Int J Biol Macromol
. 2018 Mar;
114:114-123.
PMID: 29572137
GADD45β is selectively and constitutively expressed in Multiple Myeloma cells, and this expression correlates with an unfavourable clinical outcome. GADD45β physically interacts with the JNK kinase, MKK7, inhibiting its activity...
8.
Capece D, DAndrea D, Verzella D, Tornatore L, Begalli F, Bennett J, et al.
Cell Death Differ
. 2018 Mar;
25(4):642-644.
PMID: 29511335
No abstract available.
9.
Verzella D, Bennett J, Fischietti M, Thotakura A, Recordati C, Pasqualini F, et al.
Cancer Res
. 2017 Dec;
78(5):1275-1292.
PMID: 29279355
T-cell exclusion from the tumor microenvironment (TME) is a major barrier to overcoming immune escape. Here, we identify a myeloid-intrinsic mechanism governed by the NF-κB effector molecule GADD45β that restricts...
10.
Bennett J, Capece D, Begalli F, Verzella D, DAndrea D, Tornatore L, et al.
Int J Biochem Cell Biol
. 2017 Dec;
95:108-112.
PMID: 29277662
Constitutive NF-κB signalling has been implicated in the pathogenesis of most human malignancies and virtually all non-malignant pathologies. Accordingly, the NF-κB pathway has been aggressively pursued as an attractive therapeutic...